Results 21 to 30 of about 8,924,942 (310)

SS/SW BASE PAIRS ARE THE ONLY BASE PAIRS INVOLVED IN LONG-RANGE RNA TERTIARY MOTIFS

open access: yesJournal of Bioinformatics and Genomics, 2020
The structure of noncoding RNAs largely determines their functions. With the rapid growth of experimental data on the RNA secondary structures, the task of predicting its spatial structure becomes the most urgent task of RNA bioinformatics.
Manakov, A.K.   +2 more
doaj   +1 more source

Structural and dynamic mechanisms for coupled folding and tRNA recognition of a translational T-box riboswitch

open access: yesNature Communications, 2023
T-box riboswitches are unique riboregulators where gene regulation is mediated through interactions between two highly structured RNAs. Despite extensive structural insights, how RNA-RNA interactions drive the folding and structural transitions of T-box ...
Xiaolin Niu   +5 more
doaj   +1 more source

RNA STRUCTURAL SEGMENTATION [PDF]

open access: yes, 2009
We describe several dynamic programming segmentation algorithms to segment RNA secondary and tertiary structures into distinct domains. For this purpose, we consider fitness functions that variously depend on (i) base pairing probabilities in the Boltzmann low energy ensemble of structures, (ii) contact maps inferred from 3-dimensional structures, and (
Iván Dotú   +3 more
openaire   +3 more sources

RNA structure

open access: yesCurrent Opinion in Structural Biology, 1998
New information concerning RNA structure is accumulating at an ever increasing rate-from short helices with mismatched bases of 5S rRNA and complex RNA aptamers. The importance of recurring structural motifs, ion binding, and the kinetics and energetics of folding in RNA structure and function is now being recognized and addressed.
Conn, Graeme L., Draper, David E.
openaire   +3 more sources

Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism [PDF]

open access: yes, 2013
Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe.
Richard M. Elliott   +16 more
core   +1 more source

An RNA Thermometer Activity of the West Nile Virus Genomic 3′-Terminal Stem-Loop Element Modulates Viral Replication Efficiency during Host Switching

open access: yesViruses, 2020
The 3′-terminal stem-loop (3′SL) of the RNA genome of the flavivirus West Nile (WNV) harbors, in its stem, one of the sequence elements that are required for genome cyclization.
Alexandra Meyer   +7 more
doaj   +1 more source

Recent Advances in Targeted Nanocarriers for the Management of Triple Negative Breast Cancer

open access: yesPharmaceutics, 2023
Triple-negative breast cancer (TNBC) is a life-threatening form of breast cancer which has been found to account for 15% of all the subtypes of breast cancer.
Rajesh Pradhan   +5 more
doaj   +1 more source

Cooperativity and Interdependency between RNA Structure and RNA–RNA Interactions

open access: yesNon-Coding RNA, 2021
Complex RNA–RNA interactions are increasingly known to play key roles in numerous biological processes from gene expression control to ribonucleoprotein granule formation.
Ilias Skeparnias, Jinwei Zhang
doaj   +1 more source

A comprehensive comparison of comparative RNA structure prediction approaches [PDF]

open access: yes, 2004
Gardner PP, Giegerich R. A comprehensive comparison of comparative RNA structure prediction approaches. BMC Bioinformatics. 2004;5(1): 140.Background: An increasing number of researchers have released novel RNA structure analysis and prediction ...
Giegerich, R.   +7 more
core   +1 more source

Molecular Characterization of Reduced Susceptibility to Biocides in Clinical Isolates of Acinetobacter baumannii

open access: yesFrontiers in Microbiology, 2017
Active efflux is regarded as a common mechanism for antibiotic and biocide resistance. However, the role of many drug efflux pumps in biocide resistance in Acinetobacter baumannii remains unknown. Using biocide-resistant A.
Fei Lin   +8 more
doaj   +1 more source

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