Results 281 to 290 of about 9,541,112 (326)

Structures of RNA Switches: Insight into Molecular Recognition and Tertiary Structure

Angewandte Chemie International Edition, 2007
AbstractRNA switches (riboswitches) have important functions in gene regulation. They comprise an aptamer domain, which is responsible for ligand binding, and an expression platform that transmits the ligand‐binding state of the aptamer domain through a conformational change.
Harald, Schwalbe, Janina, Buck, Boris, Fürtig, Jonas, Noeske, Jens, Wöhnert   +4 more
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Tertiary structure and function of transfer-RNA

Biophysik, 1972
In analogy to the globular protein structures the predominant stabilization factor of which is surface energy a compact model with the smallest possible surface of the tertiary structure of t-RNA is suggested. The principle of folding is — according to the clover leaf model — the superposition of the three leaves.
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Quaternion representation of RNA sequences and tertiary structures

Biosystems, 1993
A quaternion representation of nucleotides is proposed, with representation of RNA sequences by vectors whose elements are quaternions. Structure and transition matrices in quaternion representation are defined. Correspondence between diagrammatic technique in complex-number and quaternion representation of nucleotides is delineated.
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Influence of hydrostatic pressure and cosolutes on RNA tertiary structure.

Journal of the American Chemical Society, 2007
RNAs fold into complex three-dimensional structures that are critical to their various biological functions.
Christopher D Downey, Ryan L. Crisman, T. Randolph, A. Pardi   +3 more
semanticscholar   +3 more sources

Energetics and Cooperativity of Tertiary Hydrogen Bonds in RNA Structure

Biochemistry, 1999
Tertiary interactions that allow RNA to fold into intricate three-dimensional structures are being identified, but little is known about the thermodynamics of individual interactions. Here we quantify the tertiary structure contributions of individual hydrogen bonds in a "ribose zipper" motif of the recently crystallized Tetrahymena group I intron P4 ...
S K, Silverman, T R, Cech
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Goal seeking in the problem of folding RNA tertiary structures

Automatic Control and Computer Sciences, 2011
It is demonstrated that the problem of ribonucleic acid (RNA) molecule folding can be represented as the optimal decision making problem of the game theory. The difference is that it is impossible to simulate (calculate) all the possible conformations (states) of the RNA chain since the problem is NP complete. Therefore, it is necessary to perform goal
S. S. Yakovlev, Arkady N. Borisov
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Prospects for Tertiary Structure Prediction of RNA Based on Secondary Structure Information

Journal of Chemical Information and Modeling, 2012
We developed a method, called RNA Assembler using Secondary Structure Information Effectively (RASSIE), for predicting RNA tertiary structures using known secondary structure information. We attempted a fragment assembly-based method that uses a secondary structure-based fragment library.
Satoshi Yamasaki, Shugo Nakamura, Kazuhiko Fukui   +2 more
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Analysis of the tertiary structure of bacterial RNase P RNA

Molecular Biology Reports, 1996
The ubiquitous occurrence of ribonuclease P (RNase P) as a ribonucleoprotein and the catalytic properties of bacterial RNase P RNAs indicate that RNA fulfills an ancient and important role in the function of this enzyme. This review focuses on efforts to determine the structure of the bacterial RNase P RNA ribozyme. Phylogenetic comparative analysis of
M E, Harris, N R, Pace
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Tertiary Structure Prediction of RNA–RNA Complexes Using a Secondary Structure and Fragment-Based Method

Journal of Chemical Information and Modeling, 2014
A method has been developed for predicting the tertiary structures of RNA-RNA complex structures using secondary structure information and a fragment assembly algorithm. The linker base pair and secondary structure potential derived from the secondary structure information are particularly useful for prediction.
Satoshi Yamasaki, Takatsugu Hirokawa, Kiyoshi Asai, Kazuhiko Fukui   +3 more
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RNA Tertiary Structure and Protein Recognition in an L11-RNA Complex

2014
This chapter relates the intricate architecture of the L11-RNA complex to previous studies that delineated crucial features of the RNA tertiary structure and protein-RNA interface. In describing the structure, it is interesting to note how conservation and variation of different nucleotides and amino acids serve as a guide to critical features of the ...
David E. Draper, Graeme L. Conn, Apostolos G. Gittis, Debraj Guhathakurta, Eaton E. Lattman, Luis Reynaldo   +5 more
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