Localisation of RNAs into the germ plasm of vitellogenic xenopus oocytes [PDF]
We have studied the localisation of mRNAs in full-grown Xenopus laevis oocytes by injecting fluorescent RNAs, followed by confocal microscopy of the oocyte cortex.
Nijjar, Sarbjit +5 more
core +1 more source
Ultrastructural analysis of the functional domains in FMRP using primary hippocampal mouse neurons
Fragile X syndrome is caused by lack of the protein FMRP. FMRP mediates mRNA binding, dendritic mRNA transport and translational control at spines.
Josien Levenga +7 more
doaj +1 more source
An Endoribonuclease Functionally Linked to Perinuclear mRNP Quality Control Associates with the Nuclear Pore Complexes [PDF]
Nuclear mRNA export is a crucial step in eukaryotic gene expression, which is in yeast coupled to cotranscriptional messenger ribonucleoprotein particle ( mRNP) assembly and surveillance.
Attila Rácz +17 more
core +1 more source
Differential polyadenylation of ribosomal RNA during post-transcriptional processing in Leishmania. [PDF]
The protozoan parasite Leishmania belongs to the most ancient eukaryotic lineages and this is reflected in several distinctive biological features, such as eukaryotic polycistronic transcription and RNA trans-splicing.
Laurent, T. +31 more
core +1 more source
Sensitive extraction-free SARS-CoV-2 RNA virus detection using a chelating resin
Summary: Current conventional detection of SARS-CoV-2 involves collection of a patient’s sample with a nasopharyngeal swab, storage of the swab during transport in a viral transport medium, extraction of RNA, and quantitative reverse transcription PCR ...
Bin Guan +6 more
doaj +1 more source
Transport of Proteins and RNAs in and out of the Nucleus [PDF]
We are most grateful to Dr. Ueli Aebi and Dr. Brian Burke for the drawing of the NPC on which Figure 2Figure 2 is based, and to an anonymous reviewer who provided suggestions for condensing and improving the manuscript. We hope colleagues will accept our sincere apologies for omitting, due to space limitations, many citations of very important ...
Nakielny, Sara, Dreyfuss, Gideon
openaire +2 more sources
A New Cell-to-Cell Transport Model for Potexviruses
In the last five years, we have gained significant insight into the role of the Potexvirus proteins in virus movement and RNA silencing. Potexviruses require three movement proteins, named triple gene block (TGB)p1, TGBp2, andTGBp3, and the viral coat ...
Jeanmarie Verchot-Lubicz
doaj +1 more source
RNA TRANSPORT AND LOCAL CONTROL OF TRANSLATION [PDF]
In eukaryotes, the entwined pathways of RNA transport and local translational regulation are key determinants in the spatio-temporal articulation of gene expression. One of the main advantages of this mechanism over transcriptional control in the nucleus lies in the fact that it endows local sites with independent decision-making authority, a ...
Stefan, Kindler +3 more
openaire +2 more sources
Structural basis for the sequence-specific RNA-recognition mechanism of human CUG-BP1 RRM3 [PDF]
The CUG-binding protein 1 (CUG-BP1) is a member of the CUG-BP1 and ETR-like factors (CELF) family or the Bruno-like family and is involved in the control of splicing, translation and mRNA degradation.
Kanako Kuwasako +27 more
core +1 more source
Coalescence of the sites of cowpea mosaic virus RNA replication into a cytopathic structure [PDF]
Cowpea mosaic virus (CPMV) replication induces an extensive proliferation of endoplasmic reticulum (ER) membranes, leading to the formation of small membranous vesicles where viral RNA replication takes place.
Carette, J.E. +3 more
core +1 more source

