Results 41 to 50 of about 531,517 (296)
A membrane transporter for tryptophan composed of RNA [PDF]
RNA, 2004 We have incorporated an RNA binding site for the biological amino acid tryptophan within an RNA complex with affinity for phospholipid bilayer membranes. The resulting RNA (9:10Trp) creates a selective route through the bilayer for the amino acid. Binding and enhanced tryptophan permeability are nonlinear in RNA concentration, suggesting that RNA ...
Teresa, Janas +2 more
openaire +2 more sources
Conservation of the RNA Transport Machineries and Their Coupling to Translation Control across Eukaryotes [PDF]
, 2012 Restriction of proteins to discrete subcellular regions is a common mechanism to establish cellular asymmetries and depends on a coordinated program of mRNA localization and translation control.
Suter, Beat, Vazquez-Pianzola, Paula
core +1 more source
eLife, 2015 Microsatellite expansions are the leading cause of numerous neurodegenerative disorders. Here we demonstrate that GGGGCC and CAG microsatellite repeat RNAs associated with C9orf72 in amyotrophic lateral sclerosis/frontotemporal dementia and with ...
Alondra Schweizer Burguete +5 more
doaj +1 more source
The Noc proteins involved in ribosome synthesis and export contain divergent HEAT repeats [PDF]
, 2004 The Noc1-4p proteins were previously reported to be involved in intranuclear and nucleocytoplasmic transport of pre-ribosomes. Using fold recognition and structural modeling, we show that Noc1-4p are largely comprised of alpha-helical repeats similar to ...
Tollervey, D, Dlakic, M
core +1 more source
Role of nucleocytoplasmic RNA transport during the life cycle of retroviruses
Frontiers in Microbiology, 2012 Retroviruses have evolved mechanisms for transporting their intron-containing RNAs (including genomic and messenger RNAs, which encode virion components) from the nucleus to the cytoplasm of the infected cell.
Hisatoshi eShida
doaj +1 more source
Impact of collection method on assessment of semen HIV RNA viral load. [PDF]
PLoS ONE, 2011 The blood HIV RNA viral load is the best-defined predictor of HIV transmission, in part due to ease of measurement and the correlation of blood and genital tract (semen or cervico-vaginal) viral load, although recent studies found semen HIV RNA ...
Brendan J W Osborne +4 more
doaj +1 more source
Xp54 and related (DDX6-like) RNA helicases : roles in messenger RNP assembly, translation regulation and RNA degradation [PDF]
, 2006 The DEAD-box RNA helicase Xp54 is an integral component of the messenger ribonucleoprotein (mRNP) particles of Xenopus oocytes. In oocytes, several abundant proteins bind pre-mRNA transcripts to modulate nuclear export, RNA stability and translational ...
Weston, A, Sommerville, John
core +1 more source
Long-Distance Transport of Prosystemin Messenger RNA in Tomato
Frontiers in Plant Science, 2017 Main conclusion: The transcripts of transgenic prosystemin (PS) gene are mobile and the PS mRNA can be translated into protein in tomato and tobacco plants.
Haiyan Zhang, Yuanyuan Hu, Yuanyuan Hu
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Structural studies of RNA localisation signals [PDF]
, 2009 Asymmetric localisation of cytoplasmic mRNA in the cell appears in a variety of organisms and is important for establishment of spatially differential expression of genes.
Ringel, I.
core