Results 91 to 100 of about 3,158,683 (345)
Viruses, 2019 Mumps virus (MuV) is a neurotropic non-segmented, negative-stranded, enveloped RNA virus in the Paramyxovirus family. The 15.4 kb genome encodes seven genes, including the V/P, which encodes, among other proteins, the V protein.
Tahir Malik +3 more
doaj +1 more source
Viruses, 2020 We report on a novel RNA virus infecting the wasp Lysiphlebus fabarum, a parasitoid of aphids. This virus, tentatively named “Lysiphlebus fabarum virus” (LysV), was discovered in transcriptome sequences of wasps from an experimental evolution
Martina N. Lüthi +2 more
doaj +1 more source
PLoS ONE, 2015 RIG-I pathway signaling of innate immunity against RNA virus infection is organized between the ER and mitochondria on a subdomain of the ER called the mitochondrial-associated ER membrane (MAM).
Stacy M. Horner +4 more
semanticscholar +1 more source
Respiratory virus shedding in exhaled breath and efficacy of face masks
Nature Network Boston, 2020 We identified seasonal human coronaviruses, influenza viruses and rhinoviruses in exhaled breath and coughs of children and adults with acute respiratory illness.
Nancy H. L. Leung +13 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo +11 more
wiley +1 more source
RNA Virus Reassortment: An Evolutionary Mechanism for Host Jumps and Immune Evasion
PLoS Pathogens, 2015 Reassortment is an evolutionary mechanism of segmented RNA viruses that plays an important but ill-defined role in virus emergence and interspecies transmission.
D. Vijaykrishna +2 more
semanticscholar +1 more source
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
AN INSIGHT INTO THE LEISHMANIA RNA VIRUS
Indian Journal of Medical Microbiology, 2007 Leishmania RNA virus is an ancient virus that has coevolved with its protozoan host. The purpose of this article is to convey current understanding of Leishmania RNA virus as it has emerged over the past decade. The potential of the virus to play a role in modulating parasite virulence is also discussed.
A Deep, V Gupta
openaire +3 more sources
Novel Viruses in Mosquitoes from Brazilian Pantanal
Viruses, 2019 Viruses are ubiquitous and diverse microorganisms arising as a result of interactions within their vertebrate and invertebrate hosts. Here we report the presence of different viruses in the salivary glands of 1657 mosquitoes classified over 28 culicinae ...
Laura Marina Siqueira Maia +5 more
doaj +1 more source