Results 31 to 40 of about 815,962 (317)

Tudor-SN Promotes Early Replication of Dengue Virus in the Aedes aegypti Midgut

iScience, 2020
Summary: Diseases caused by mosquito-borne viruses have been on the rise for the last decades, and novel methods aiming to use laboratory-engineered mosquitoes that are incapable of carrying viruses have been developed to reduce pathogen transmission ...
Sarah Hélène Merkling, Vincent Raquin, Stéphanie Dabo, Annabelle Henrion-Lacritick, Hervé Blanc, Isabelle Moltini-Conclois, Lionel Frangeul, Hugo Varet, Maria-Carla Saleh, Louis Lambrechts   +9 more
doaj   +1 more source

Lipids and RNA virus replication [PDF]

Current Opinion in Virology, 2014
Most viruses rely heavily on their host machinery to successfully replicate their genome and produce new virus particles. Recently, the interaction of positive-strand RNA viruses with the lipid biosynthetic and transport machinery has been the subject of intense investigation.
Kouacou V, Konan, Lorena, Sanchez-Felipe
openaire   +2 more sources

Inhibition of the foot-and-mouth disease virus subgenomic replicon by RNA aptamers. [PDF]

, 2014
We have previously documented the inhibitory activity of RNA aptamers to the RNA-dependent RNA polymerase of foot-and-mouth disease virus (3D(pol)). Here we report their modification and use with a subgenomic replicon incorporating GFP (pGFP-PAC replicon)
Forrest, S, Lear, Z, Ryan, M., Herod, M, Forrest, S., Ryan, M, Stonehouse, N.J., Rowlands, DJ, Herod, M.R., Stonehouse, NJ, Lear, Z., Rowlands, D.J.   +11 more
core   +1 more source

Genome-Wide Profiling of Cervical RNA-Binding Proteins Identifies Human Papillomavirus Regulation of RNASEH2A Expression by Viral E7 and E2F1

mBio, 2019
RNA-binding proteins (RBPs) control mRNA processing, stability, transport, editing, and translation. We recently conducted transcriptome analyses comparing normal (i.e., healthy) cervical tissue samples with human papillomavirus (HPV)-positive cervical ...
Junfen Xu, Habin Liu, Yanqin Yang, Xiaohong Wang, Poching Liu, Yang Li, Craig Meyers, Nilam Sanjib Banerjee, Hsu-Kun Wang, Maggie Cam, Weiguo Lu, Louise T. Chow, Xing Xie, Jun Zhu, Zhi-Ming Zheng   +14 more
doaj   +1 more source

RNA regulatory processes in RNA virus biology

WIREs RNA, 2019
AbstractNumerous post‐transcriptional RNA processes play a major role in regulating the quantity, quality and diversity of gene expression in the cell. These include RNA processing events such as capping, splicing, polyadenylation and modification, but also aspects such as RNA localization, decay, translation, and non‐coding RNA‐associated regulation ...
Shaun T. Cross, Daniel Michalski, Megan R. Miller, Jeffrey Wilusz   +3 more
openaire   +3 more sources

Epistasis and the Adaptability of an RNA Virus [PDF]

Genetics, 2005
Abstract We have explored the patterns of fitness recovery in the vesicular stomatitis RNA virus. We show that, in our experimental setting, reversions to the wild-type genotype were rare and fitness recovery was at least partially driven by compensatory mutations.
Rafael, Sanjuán, José M, Cuevas, Andrés, Moya, Santiago F, Elena   +3 more
openaire   +2 more sources

The splicing factor proline-glutamine rich (SFPQ/PSF) is involved in influenza virus transcription. [PDF]

, 2011
The influenza A virus RNA polymerase is a heterotrimeric complex responsible for viral genome transcription and replication in the nucleus of infected cells. We recently carried out a proteomic analysis of purified polymerase expressed in human cells and
Juan Ortín, Landeras-Bueno, Sara, Jorba, N, Sara Landeras-Bueno, Ortín Juan, Pérez-Cidoncha, Maite, Pérez-Cidoncha, M, Núria Jorba, Landeras-Bueno Sara, Pérez-Cidoncha Maite, Landeras-Bueno, S, Ortín, J, Ortín, Juan, Jorba, Núria, Maite Pérez-Cidoncha, Jorba Núria   +15 more
core   +1 more source

Alleviation of Postharvest Skin Dimpling of MN55 Apple Fruit and a Possible Association with Apple stem pitting virus

HortScience, 2021
MN55 is an apple (Malus ×domestica Borkh.) cultivar recently released by the University of Minnesota apple breeding program, with fruit marketed in the U.S. as Rave®. When stored for 4 months at 0 to 4 °C, MN55 fruit can develop several storage disorders,
Cindy B.S. Tong, Hsueh-Yuan Chang, James J. Luby, David Bedford, Benham E.L. Lockhart, Roy G. Kiambi, Dimitre Mollov   +6 more
doaj   +1 more source

A twist in the tail : SHAPE mapping of long-range interactions and structural rearrangements of RNA elements involved in HCV replication [PDF]

, 2011
The RNA structure and long-range interactions of the SL9266 cis-acting replication element located within the NS5B coding region of hepatitis C virus (HCV) were determined using selective 2′-hydroxyl acylation analysed by primer extension.
Tuplin, Andrew, Struthers, Madeleine, Struthers, M., Andrew Tuplin, Tuplin, A., Struthers, M, Madeleine Struthers, Simmonds, Peter, David J. Evans, Tuplin, A, Evans, DJ, Peter Simmonds, Evans, David J., Simmonds, P., Evans, D. J., Simmonds, P   +15 more
core   +1 more source

Cellular Internalization And RNA Regulation Of RNA Virus

Advances In Clinical And Medical Research, 2020
Biological responses are regulated by various molecular networks. It is significantly important to reveal the mechanisms of diseases and cellular responses for the prevention and drug development. The infection mechanism of RNA virus consists of viral internalization, replication including RNA transcription, and expansion.
openaire   +1 more source