RNA interference targets arbovirus replication in Culicoides cells [PDF]
, 2013 Arboviruses are transmitted to vertebrate hosts by biting arthropod vectors such as mosquitoes, ticks and midges. These viruses replicate in both arthropods and vertebrates and are thus exposed to different antiviral responses in these organisms.
Varela, Mariana +20 more
core +1 more source
Correction to: Circular RNAs and RNase L in PKR activation and virus infection
Cell & Bioscience, 2019 In the publication of this article [1], there are a few errors in the article.
Zhi-Ming Zheng
doaj +1 more source
Role of Infectious Agents in the Etiology of Kawasaki Disease [PDF]
Pediatric Infectious Disease, 2022 Kawasaki disease (KD) is a multisystemic childhood vasculitis that predominantly affects the coronary arteries. The constellation of clinical features in KD, such as, acute onset of fever, redness of lips and oral mucosa, rash, swelling over palms and ...
Aaqib Banday +2 more
doaj +1 more source
Sequential packaging of RNA genomic segments during the assembly of Bluetongue virus. [PDF]
, 2014 Bluetongue virus (BTV), a member of the Orbivirus genus within the Reoviridae family, has a genome of 10 double-stranded RNA segments, with three distinct size classes.
Roy, Polly +3 more
core +1 more source
Circular RNAs and RNase L in PKR activation and virus infection
Cell & Bioscience, 2019 Circular RNAs (circRNAs) from back-splicing have been found in every cell and tissue. By binding to miRNAs and proteins or even by encoding small proteins, circRNAs are now emerging as important regulators in modulating transcription, RNA splicing and ...
Zhi-Ming Zheng
doaj +1 more source
Generation and characterization of a recombinant Rift Valley fever virus expressing a V5 epitope-tagged RNA-dependent RNA polymerase [PDF]
, 2011 The viral RNA-dependent RNA polymerase (RdRp; L protein) of Rift Valley fever virus (RVFV; family Bunyaviridae) is a 238 kDa protein that is crucial for the life cycle of the virus, as it catalyses both transcription of viral mRNAs and replication of the
Brennan, Benjamin +5 more
core +1 more source
Riboswitching on RNA virus replication [PDF]
Proceedings of the National Academy of Sciences, 2007 Positive-strand RNA viruses direct different virus-specific processes during their infection of host cells. Fundamental events such as viral RNA genome replication are controlled by viral regulatory RNA elements (REs). Here, we have investigated the possibility of specifically modulating the action of a viral RE using RNA aptamer technology.
Sheng, Wang, K Andrew, White
openaire +2 more sources
The influence of CpG and UpA dinucleotide frequencies on RNA virus replication and characterization of the innate cellular pathways underlying virus attenuation and enhanced replication [PDF]
, 2014 Most RNA viruses infecting mammals and other vertebrates show profound suppression of CpG and UpA dinucleotide frequencies. To investigate this functionally, mutants of the picornavirus, echovirus 7 (E7), were constructed with altered CpG and UpA ...
Atkinson, N J +5 more
core +1 more source
Tudor-SN Promotes Early Replication of Dengue Virus in the Aedes aegypti Midgut
iScience, 2020 Summary: Diseases caused by mosquito-borne viruses have been on the rise for the last decades, and novel methods aiming to use laboratory-engineered mosquitoes that are incapable of carrying viruses have been developed to reduce pathogen transmission ...
Sarah Hélène Merkling +9 more
doaj +1 more source
Inhibition of the foot-and-mouth disease virus subgenomic replicon by RNA aptamers. [PDF]
, 2014 We have previously documented the inhibitory activity of RNA aptamers to the RNA-dependent RNA polymerase of foot-and-mouth disease virus (3D(pol)). Here we report their modification and use with a subgenomic replicon incorporating GFP (pGFP-PAC replicon)
Forrest, S +11 more
core +1 more source