Results 41 to 50 of about 719,129 (168)

Multiple Regions of Kaposi’s Sarcoma-Associated Herpesvirus ORF59 RNA are Required for Its Expression Mediated by Viral ORF57 and Cellular RBM15

Viruses, 2015
KSHV ORF57 (MTA) promotes RNA stability of ORF59, a viral DNA polymerase processivity factor. Here, we show that the integrity of both ORF59 RNA ends is necessary for ORF57-mediated ORF59 expression and deletion of both 5’ and 3’ regions, or one end ...
Maria Julia Massimelli, Vladimir Majerciak, Jeong-Gu Kang, David J. Liewehr, Seth M. Steinberg, Zhi-Ming Zheng   +5 more
doaj   +1 more source

Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies

Nature Communications, 2023
In this work, Planas et al. report that Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 escape neutralization from monoclonal antibodies, and sera from vaccinated individuals with or without Omicron BA.1/2 or BA.5 breakthrough infection.
Delphine Planas, Timothée Bruel, Isabelle Staropoli, Florence Guivel-Benhassine, Françoise Porrot, Piet Maes, Ludivine Grzelak, Matthieu Prot, Said Mougari, Cyril Planchais, Julien Puech, Madelina Saliba, Riwan Sahraoui, Florent Fémy, Nathalie Morel, Jérémy Dufloo, Rafael Sanjuán, Hugo Mouquet, Emmanuel André, Laurent Hocqueloux, Etienne Simon-Loriere, David Veyer, Thierry Prazuck, Hélène Péré, Olivier Schwartz   +24 more
doaj   +1 more source

Oncogenes and RNA splicing of human tumor viruses

Emerging Microbes and Infections, 2014
Approximately 10.8% of human cancers are associated with infection by an oncogenic virus. These viruses include human papillomavirus (HPV), Epstein–Barr virus (EBV), Merkel cell polyomavirus (MCV), human T-cell leukemia virus 1 (HTLV-1), Kaposi's sarcoma-
Masahiko Ajiro, Zhi-Ming Zheng
doaj   +1 more source

The Segment Matters: Probable Reassortment of Tilapia Lake Virus (TiLV) Complicates Phylogenetic Analysis and Inference of Geographical Origin of New Isolate from Bangladesh

Viruses, 2020
Tilapia lake virus (TiLV), a negative sense RNA virus with a 10 segment genome, is an emerging threat to tilapia aquaculture worldwide, with outbreaks causing over 90% mortality reported on several continents since 2014.
Dominique L. Chaput, David Bass, Md. Mehedi Alam, Neaz Al Hasan, Grant D. Stentiford, Ronny van Aerle, Karen Moore, John P. Bignell, Mohammad Mahfujul Haque, Charles R. Tyler   +9 more
doaj   +1 more source

RNA splicing in Borna disease virus, a nonsegmented, negative-strand RNA virus [PDF]

Journal of Virology, 1994
Borna disease virus (BDV) is a nonsegmented, negative-strand RNA virus related to rhabdoviruses and paramyxoviruses. Unlike animal viruses of these two families, BDV transcribes RNAs in the nuclei of infected cells and produces high levels of transcripts containing multiple open reading frames.
P A, Schneider, A, Schneemann, W I, Lipkin   +2 more
openaire   +2 more sources

COVID-19: An up-to-date review – from morphology to pathogenesis

Indian Journal of Pathology and Microbiology, 2020
The entire world is under a devastating pandemic caused by COVID-19 with a high mortality rate. Knowledge of the viral structure, factors that help in its progression and spread, pathological findings, diagnostic methods and, treatment modalities helps ...
Amanjit Bal, Ranjan Agrawal, Pradeep Vaideeswar, Sudheer Arava, Amita Jain   +4 more
doaj   +1 more source

RNA Virus Populations as Quasispecies [PDF]

, 1992
RNA virus mutation frequencies generally approach maximum tolerable levels, and create complex indeterminate quasispecies populations in infected hosts. This usually favors extreme rates of evolution, although periods of relative stasis or equilibrium, punctuated by rapid change may also occur (as for other life forms).
J J, Holland, J C, De La Torre, D A, Steinhauer   +2 more
openaire   +2 more sources

RNA-binding proteins that inhibit RNA virus infection [PDF]

Proceedings of the National Academy of Sciences, 2007
Arrays of >5,000 Saccharomyces cerevisiae proteins were screened to identify proteins that can preferentially bind a small RNA hairpin that contains a clamped adenine motif (CAM). A CAM is required for the replication of Brome Mosaic Virus (BMV), a plant-infecting RNA virus that can replicate in S ...
Jian, Zhu, Kodetham, Gopinath, Ayaluru, Murali, Guanghui, Yi, S Diane, Hayward, Heng, Zhu, Cheng, Kao   +6 more
openaire   +2 more sources

Structural Constraints on RNA Virus Evolution [PDF]

Journal of Virology, 1999
ABSTRACT The recently discovered hepatitis G virus (HGV) or GB virus C (GBV-C) is widely distributed in human populations, and homologues such as HGV/GBV-C CPZ and GBV-A are found in a variety of different primate species.
Simmonds, P, Smith, D B
openaire   +3 more sources

A Single Point Mutation in the Mumps V Protein Alters Targeting of the Cellular STAT Pathways Resulting in Virus Attenuation

Viruses, 2019
Mumps virus (MuV) is a neurotropic non-segmented, negative-stranded, enveloped RNA virus in the Paramyxovirus family. The 15.4 kb genome encodes seven genes, including the V/P, which encodes, among other proteins, the V protein.
Tahir Malik, Laurie Ngo, Trent Bosma, Steven Rubin   +3 more
doaj   +1 more source