Results 11 to 20 of about 447,697 (355)
Roles of MOV10 in Animal RNA Virus Infection [PDF]
Frontiers in Veterinary Science, 2020 Animal epidemic diseases caused by RNA viruses are the primary threat to the livestock industry, and understanding the mechanisms of RNA virus clearance from target cells is critical to establish an effective method to reduce economic losses. As an SF-1, ATP-dependent RNA helicase in the UPF1p family, MOV10 participates in the RNA degradation of ...
Xueming Liu, Feng Su, Yunliang Jiang
openaire +4 more sources
Hepatitis C and HIV detection by blood RNA-sequencing in cohort of smokers
Scientific Reports, 2023 Detection of viruses by RNA and DNA sequencing has improved the understanding of the human virome. We sought to identify blood viral signatures through secondary use of RNA-sequencing (RNA-seq) data in a large study cohort.
Jarrett D. Morrow +6 more
doaj +1 more source
RNA-binding proteins that inhibit RNA virus infection [PDF]
Proceedings of the National Academy of Sciences, 2007 Arrays of >5,000 Saccharomyces cerevisiae proteins were screened to identify proteins that can preferentially bind a small RNA hairpin that contains a clamped adenine motif (CAM). A CAM is required for the replication of Brome Mosaic Virus (BMV), a plant-infecting RNA virus that can replicate in S ...
Jian Zhu +6 more
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Ribosomal control in RNA virus-infected cells
Frontiers in Microbiology, 2022 Viruses are strictly intracellular parasites requiring host cellular functions to complete their reproduction cycle involving virus infection of host cell, viral genome replication, viral protein translation, and virion release. Ribosomes are protein synthesis factories in cells, and viruses need to manipulate ribosomes to complete their protein ...
Xiao Wang +3 more
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Therapeutic Interfering Particles Exploiting Viral Replication and Assembly Mechanisms Show Promising Performance: A Modelling Study [PDF]
Scientific Reports, 11, 23847 (2021), 2021 Defective interfering particles arise spontaneously during a viral infection as mutants lacking essential parts of the viral genome. Their ability to replicate in the presence of the wild-type (WT) virus (at the expense of viable viral particles) is mimicked and exploited by therapeutic interfering particles.
arxiv +1 more source
Nature Communications, 2023 Selective autophagy is a double-edged sword in antiviral immunity and regulated by various autophagy receptors. However, it remains unclear how to balance the opposite roles by one autophagy receptor.
Xin Tong +8 more
doaj +1 more source
Integrative analysis of ATAC-seq and RNA-seq for cells infected by human T-cell leukemia virus type 1 [PDF]
PLOS Comput. Biol. 21(1), e1012690 (2025), 2023 Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy (HAM) after a long latent period in a fraction of infected individuals. These HTLV-1-infected cells typically have phenotypes similar to that of CD4${^+}$ T cells, but the cell status is not well understood.
arxiv +1 more source
Plant RNA Regulatory Network and RNA Granules in Virus Infection [PDF]
Frontiers in Plant Science, 2017 Regulation of post-transcriptional gene expression on mRNA level in eukaryotic cells includes translocation, translation, translational repression, storage, mRNA decay, RNA silencing, and nonsense-mediated decay. These processes are associated with various RNA-binding proteins and cytoplasmic ribonucleoprotein complexes many of which are conserved ...
Makinen, Kristiina +2 more
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RNA-binding protein CPEB1 remodels host and viral RNA landscapes. [PDF]
, 2016 Host and virus interactions occurring at the post-transcriptional level are critical for infection but remain poorly understood. Here, we performed comprehensive transcriptome-wide analyses revealing that human cytomegalovirus (HCMV) infection results in
Aigner, Stefan +17 more
core +2 more sources
Potential Application of the CRISPR/Cas9 System against Herpesvirus Infections. [PDF]
, 2018 The CRISPR/Cas9 system has been applied in the genome editing and disruption of latent infections for herpesviruses such as the herpes simplex virus, Epsteinā»Barr virus, cytomegalovirus, and Kaposi's sarcoma-associated herpesvirus.
Chen, Yuan-Chuan +3 more
core +5 more sources