Results 31 to 40 of about 445,400 (250)
Molecular Insights into the Flavivirus Replication Complex
Flaviviruses are vector-borne RNA viruses, many of which are clinically relevant human viral pathogens, such as dengue, Zika, Japanese encephalitis, West Nile and yellow fever viruses.
Kaïn van den Elsen +2 more
doaj +1 more source
Exosomes and Their Role in the Life Cycle and Pathogenesis of RNA Viruses
Exosomes are membrane-enclosed vesicles actively released into the extracellular space, whose content reflect the physiological/pathological state of the cells they originate from.
Harendra Singh Chahar +2 more
doaj +1 more source
Plant RNA Regulatory Network and RNA Granules in Virus Infection [PDF]
Regulation of post-transcriptional gene expression on mRNA level in eukaryotic cells includes translocation, translation, translational repression, storage, mRNA decay, RNA silencing, and nonsense-mediated decay. These processes are associated with various RNA-binding proteins and cytoplasmic ribonucleoprotein complexes many of which are conserved ...
Kristiina Mäkinen +2 more
openaire +3 more sources
RNA Viruses: ROS-Mediated Cell Death
Reactive oxygen species (ROS) are well known for being both beneficial and deleterious. The main thrust of this review is to investigate the role of ROS in ribonucleic acid (RNA) virus pathogenesis.
Mohammad Latif Reshi +2 more
doaj +1 more source
An RNA virus can adapt to the multiplicity of infection.
RNA viruses evolve as complex distributions of mutants termed viral quasispecies. For this reason it is relevant to explore those environmental parameters that favour the selective advantage of some viral subpopulations over others. In the present study we provide direct evidence that the relative fitness of two competing viral subpopulations may ...
Sevilla, Noemi +4 more
openaire +3 more sources
DDX17 (DEAD-box RNA helicase 17) is an essential RNA helicase and regulatory ATPase in host cells, extensively involved in various cellular processes during viral infections, such as RNA splicing, transcriptional regulation, and post-transcriptional ...
Yuting Cheng +7 more
doaj +1 more source
Infection by (re-)emerging RNA arboviruses including Chikungunya virus (CHIKV) and Mayaro virus primarily cause acute febrile disease and transient polyarthralgia. However, in a significant subset of infected individuals, debilitating arthralgia persists
Fabian Pott +6 more
doaj +1 more source
Mycoviruses as Triggers and Targets of RNA Silencing in White Mold Fungus Sclerotinia sclerotiorum
This study aimed to demonstrate the existence of antiviral RNA silencing mechanisms in Sclerotinia sclerotiorum by infecting wild-type and RNA-silencing-deficient strains of the fungus with an RNA virus and a DNA virus.
Pauline Mochama +3 more
doaj +1 more source
Computer-designed orthogonal RNA aptamers programmed to recognize Ebola virus glycoproteins
Ebola virus (EBOV), a member of the filovirus family, is an enveloped negative-sense RNA virus that causes lethal infections in humans and primates.
Yue Teng +6 more
doaj +1 more source
Background: The main threat to human health is infectious disease. For the treatment of infections with RNA viruses, there are hardly any antiviral drugs in the market.
Gajala Deethamvali Ghouse Peer +4 more
doaj +1 more source

