Results 31 to 40 of about 441,359 (251)
Molecular Insights into the Flavivirus Replication Complex
Viruses, 2021 Flaviviruses are vector-borne RNA viruses, many of which are clinically relevant human viral pathogens, such as dengue, Zika, Japanese encephalitis, West Nile and yellow fever viruses.
Kaïn van den Elsen +2 more
doaj +1 more source
Exosomes and Their Role in the Life Cycle and Pathogenesis of RNA Viruses
Viruses, 2015 Exosomes are membrane-enclosed vesicles actively released into the extracellular space, whose content reflect the physiological/pathological state of the cells they originate from.
Harendra Singh Chahar +2 more
doaj +1 more source
An RNA virus can adapt to the multiplicity of infection.
Journal of General Virology, 1998 RNA viruses evolve as complex distributions of mutants termed viral quasispecies. For this reason it is relevant to explore those environmental parameters that favour the selective advantage of some viral subpopulations over others. In the present study we provide direct evidence that the relative fitness of two competing viral subpopulations may ...
Sevilla, Noemi +4 more
openaire +3 more sources
RNA Viruses: ROS-Mediated Cell Death
International Journal of Cell Biology, 2014 Reactive oxygen species (ROS) are well known for being both beneficial and deleterious. The main thrust of this review is to investigate the role of ROS in ribonucleic acid (RNA) virus pathogenesis.
Mohammad Latif Reshi +2 more
doaj +1 more source
Innate Immune Response to RNA Virus Infections
Uirusu, 2011 Viral RNA is recognized by RIG-I-like receptors and Toll-like receptors. RIG-I is a cytoplasmic viral RNA sensor. High Mobility Group Box (HMGB) proteins and DExD/H box RNA helicases, such as DDX3 and 60, associate with viral RNA. Those proteins promotes the RIG-I binding to viral RNA. RIG-I triggers the signal via IPS-1 adaptor molecule to induce type
OSHIUMI, Hiroyuki +2 more
openaire +3 more sources
VirulenceDDX17 (DEAD-box RNA helicase 17) is an essential RNA helicase and regulatory ATPase in host cells, extensively involved in various cellular processes during viral infections, such as RNA splicing, transcriptional regulation, and post-transcriptional ...
Yuting Cheng +7 more
doaj +1 more source
Emerging Microbes and Infections, 2021 Infection by (re-)emerging RNA arboviruses including Chikungunya virus (CHIKV) and Mayaro virus primarily cause acute febrile disease and transient polyarthralgia. However, in a significant subset of infected individuals, debilitating arthralgia persists
Fabian Pott +6 more
doaj +1 more source
Computer-designed orthogonal RNA aptamers programmed to recognize Ebola virus glycoproteins
Biosafety and Health, 2019 Ebola virus (EBOV), a member of the filovirus family, is an enveloped negative-sense RNA virus that causes lethal infections in humans and primates.
Yue Teng +6 more
doaj +1 more source
Mycoviruses as Triggers and Targets of RNA Silencing in White Mold Fungus Sclerotinia sclerotiorum
Viruses, 2018 This study aimed to demonstrate the existence of antiviral RNA silencing mechanisms in Sclerotinia sclerotiorum by infecting wild-type and RNA-silencing-deficient strains of the fungus with an RNA virus and a DNA virus.
Pauline Mochama +3 more
doaj +1 more source
Food Chemistry Advances, 2023 Background: The main threat to human health is infectious disease. For the treatment of infections with RNA viruses, there are hardly any antiviral drugs in the market.
Gajala Deethamvali Ghouse Peer +4 more
doaj +1 more source