Results 41 to 50 of about 2,976,975 (155)

Single-cell analysis of arthritogenic alphavirus-infected human synovial fibroblasts links low abundance of viral RNA to induction of innate immunity and arthralgia-associated gene expression

Emerging Microbes and Infections, 2021
Infection by (re-)emerging RNA arboviruses including Chikungunya virus (CHIKV) and Mayaro virus primarily cause acute febrile disease and transient polyarthralgia. However, in a significant subset of infected individuals, debilitating arthralgia persists
Fabian Pott, Dylan Postmus, Richard J. P. Brown, Emanuel Wyler, Elena Neumann, Markus Landthaler, Christine Goffinet   +6 more
doaj   +1 more source

Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasion

Nature Communications
The unceasing circulation of SARS-CoV-2 leads to the continuous emergence of novel viral sublineages. Here, we isolate and characterize XBB.1, XBB.1.5, XBB.1.9.1, XBB.1.16.1, EG.5.1.1, EG.5.1.3, XBF, BA.2.86.1 and JN.1 variants, representing >80% of ...
Delphine Planas, Isabelle Staropoli, Vincent Michel, Frederic Lemoine, Flora Donati, Matthieu Prot, Francoise Porrot, Florence Guivel-Benhassine, Banujaa Jeyarajah, Angela Brisebarre, Océane Dehan, Léa Avon, William Henry Bolland, Mathieu Hubert, Julian Buchrieser, Thibault Vanhoucke, Pierre Rosenbaum, David Veyer, Hélène Péré, Bruno Lina, Sophie Trouillet-Assant, Laurent Hocqueloux, Thierry Prazuck, Etienne Simon-Loriere, Olivier Schwartz   +24 more
doaj   +1 more source

Temperature-dependent replication and sensitivity to innate immunity of human coronavirus HKU1

Nature Communications
The human coronavirus HKU1, causing common colds and occasionally severe illness, remains largely uncharacterized because it has not been successfully grown on immortalized cells.
Julian Buchrieser, Eva Thuillier, Jeanne Postal, Amélie Wileveau, Florence Guivel-Benhassine, Isabelle Staropoli, Nell Saunders, Delphine Planas, Jamie Sugrue, Vincent Bondet, Ignacio Fernández, François Bontems, Françoise Porrot, Chloé Petiot, Matthieu Prot, Martin Jungbauer-Groznica, Laurence Arowas, Vincent Michel, Catherine Blanc, Sophie Trouillet-Assant, Timothée Bruel, Félix A. Rey, Marie-Anne Rameix-Welti, Nicoletta Casartelli, Arnaud Fontanet, Michael White, Darragh Duffy, Etienne Simon-Lorière, Olivier Schwartz   +28 more
doaj   +1 more source

Citrus fruits, vitamin D, and the RNA virus: A correlation and meta-analysis study in Taiwan and the USA

Food Chemistry Advances, 2023
Background: The main threat to human health is infectious disease. For the treatment of infections with RNA viruses, there are hardly any antiviral drugs in the market.
Gajala Deethamvali Ghouse Peer, Elcio Leal, V. Samuel Raj, Chung-Ming Chang, Ramendra Pati Pandey   +4 more
doaj   +1 more source

Bluetongue virus non-structural protein 1 is a positive regulator of viral protein synthesis. [PDF]

, 2012
BACKGROUND: Bluetongue virus (BTV) is a double-stranded RNA (dsRNA) virus of the Reoviridae family, which encodes its genes in ten linear dsRNA segments.
Roy Polly, Boyce, Mark, Roy, Polly, Celma, Cristina CP, Cristina C P Celma, Boyce Mark, Mark Boyce, Polly Roy, Celma Cristina C P   +8 more
core   +1 more source

Prevalence of dengue, chikungunya and zika viruses in blood donors in Kunming, China

Zhongguo shuxue zazhi
Objective To investigate the prevalence of zika virus (ZIKV), dengue virus (DENV) and chikungunya virus (CHIKV) infections in blood donors in Kunming, China.
ZHANG Zhihui, LI Qian, PENG Mozhen, LUO Zhen, CHEN Lu, GAO Lili, CUN Wei, DU Xia   +7 more
doaj   +1 more source

Detection of Multiple Potato Viruses in the Field Suggests Synergistic Interactions among Potato Viruses in Pakistan

The Plant Pathology Journal, 2014
Viral diseases have been a major limiting factor threating sustainable potato (Solanum tuberosum L.) production in Pakistan. Surveys were conducted to serologically quantify the incidence of RNA viruses infecting potato; Potato virus X (PVX), Potato ...
Amir Hameed, Zafar Iqbal, Shaheen Asad, Shahid Mansoor   +3 more
doaj   +1 more source

Nora virus persistent infections are not affected by the RNAi machinery. [PDF]

PLoS ONE, 2009
Drosophila melanogaster is widely used to decipher the innate immune system in response to various pathogens. The innate immune response towards persistent virus infections is among the least studied in this model system. We recently discovered a picorna-
Mazen S Habayeb, Jens-Ola Ekström, Dan Hultmark   +2 more
doaj   +1 more source

Zika Virus Infection and Prolonged Viremia in Whole-Blood Specimens

Emerging Infectious Diseases, 2017
We tested whole-blood and plasma samples from immunocompetent patients who had had benign Zika virus infections and found that Zika virus RNA persisted in whole blood substantially longer than in plasma.
Jean Michel Mansuy, Catherine Mengelle, Christophe Pasquier, Sabine Chapuy-Regaud, Pierre Delobel, Guillaume Martin-Blondel, Jacques Izopet   +6 more
doaj   +1 more source

Patterns of RNA Editing in Newcastle Disease Virus Infections

Viruses, 2020
The expression of accessory non-structural proteins V and W in Newcastle disease virus (NDV) infections depends on RNA editing. These proteins are derived from frameshifts of the sequence coding for the P protein via co-transcriptional insertion of one ...
Archana Jadhav, Lele Zhao, Alice Ledda, Weiwei Liu, Chan Ding, Venugopal Nair, Luca Ferretti   +6 more
doaj   +1 more source