Results 61 to 70 of about 447,697 (355)

The impact of RNA modifications on the biology of DNA virus infection

open access: yesEuropean Journal of Cell Biology, 2022
Approximately 170 RNA modifications have been identified and these are critical for determining the fate and function of cellular RNAs. Similar to human transcripts, viral RNAs possess an extensive RNA modification landscape. While initial efforts largely focused on investigating the RNA modification landscape in the context of RNA virus infection, a ...
Suba Rajendren, John Karijolich
openaire   +3 more sources

Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasion

open access: yesNature Communications
The unceasing circulation of SARS-CoV-2 leads to the continuous emergence of novel viral sublineages. Here, we isolate and characterize XBB.1, XBB.1.5, XBB.1.9.1, XBB.1.16.1, EG.5.1.1, EG.5.1.3, XBF, BA.2.86.1 and JN.1 variants, representing >80% of ...
Delphine Planas   +24 more
doaj   +1 more source

Prevalence of dengue, chikungunya and zika viruses in blood donors in Kunming, China

open access: yesZhongguo shuxue zazhi
Objective To investigate the prevalence of zika virus (ZIKV), dengue virus (DENV) and chikungunya virus (CHIKV) infections in blood donors in Kunming, China.
ZHANG Zhihui   +7 more
doaj   +1 more source

Zika Virus Infection and Prolonged Viremia in Whole-Blood Specimens

open access: yesEmerging Infectious Diseases, 2017
We tested whole-blood and plasma samples from immunocompetent patients who had had benign Zika virus infections and found that Zika virus RNA persisted in whole blood substantially longer than in plasma.
Jean Michel Mansuy   +6 more
doaj   +1 more source

Heparan sulfate proteoglycan is an important attachment factor for cell entry of Akabane and Schmallenberg viruses [PDF]

open access: yes, 2017
Akabane (AKAV) and Schmallenberg (SBV) viruses are Orthobunyavirus transmitted by arthropod vectors with a broad cellular tropism in vitro as well as in vivo Both AKAV and SBV cause arthrogryposis-hydranencephaly syndrome in ruminants.
Horimoto, Taisuke   +6 more
core   +2 more sources

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

No two without three: Modelling dynamics of the trio RNA virus-defective interfering genomes-RNA satellite [PDF]

open access: yesarXiv, 2023
Almost all viruses, regardless of their genomic material, produce defective viral genomes (DVG) as an unavoidable byproduct of their error-prone replication. Defective interfering (DI) elements are a subgroup of DVGs that have been shown to interfere with the replication of the wild-type (WT) virus.
arxiv  

Dampening of ISGylation of RIG-I by ADAP regulates type I interferon response of macrophages to RNA virus infection.

open access: yesPLoS Pathogens
While macrophage is one of the major type I interferon (IFN-I) producers in multiple tissues during viral infections, it also serves as an important target cell for many RNA viruses. However, the regulatory mechanism for the IFN-I response of macrophages
Yan Wang   +14 more
doaj   +1 more source

Influenza Virus RNA Synthesis and the Innate Immune Response

open access: yesViruses, 2021
Infection with influenza A and B viruses results in a mild to severe respiratory tract infection. It is widely accepted that many factors affect the severity of influenza disease, including viral replication, host adaptation, innate immune signalling ...
Sabrina Weis, Aartjan J. W. te Velthuis
doaj   +1 more source

Vector competence of Aedes aegypti, Culex tarsalis, and Culex quinquefasciatus from California for Zika virus. [PDF]

open access: yes, 2018
Zika virus (ZIKV) has emerged since 2013 as a significant global human health threat following outbreaks in the Pacific Islands and rapid spread throughout South and Central America.
Barker, Christopher M   +9 more
core   +3 more sources

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