Results 111 to 120 of about 3,436,004 (333)
Transgenic resistance to PMTV and PVA provides novel insights to viral long-distance movement [PDF]
The studies in this thesis describe forms of transgenic resistance to plant viruses and how they can be used for studying viral infection cycle. S. tuberosum cv.
Germundsson, Anna
core
Meta-transcriptomics and the evolutionary biology of RNA viruses
Highlights • Meta-transcriptomics (bulk RNA-Seq) is a powerful new way to characterise viromes.• Meta-transcriptomic data are changing our understanding of virus evolution.• Invertebrates harbor an enormous phylogenetic and genomic diversity of RNA ...
M. Shi +2 more
semanticscholar +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Plant reoviruses are able to multiply in gramineae plants and delphacid vectors encountering different defense strategies with unique features. This study aims to comparatively assess alterations of small RNA (sRNA) populations in both hosts upon virus ...
Luis A. de Haro +14 more
doaj +1 more source
Sindbis virus ts103 has a mutation in glycoprotein E2 that leads to defective assembly of virions [PDF]
Sindbis virus mutant ts103 is aberrant in the assembly of virus particles. During virus budding, proper nucleocapsid-glycoprotein interactions fail to occur such that particles containing many nucleocapsids are formed, and the final yield of virus is low.
Hahn, Chang S. +4 more
core
Myxoma virus protein M029 is a dual function immunomodulator that inhibits PKR and also conscripts RHA/DHX9 to promote expanded host tropism and viral replication. [PDF]
Myxoma virus (MYXV)-encoded protein M029 is a member of the poxvirus E3 family of dsRNA-binding proteins that antagonize the cellular interferon signaling pathways.
Chan, Winnie M +4 more
core +1 more source
The diversity, evolution and origins of vertebrate RNA viruses
Highlights • A multitude of RNA viruses are present in lower vertebrates.• Fish harbor a remarkable array of RNA viruses.• RNA viruses in vertebrates generally follow the evolutionary history of their hosts.• Frequent cross-species transmission occurs on
Yong‐Zhen Zhang +3 more
semanticscholar +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Grapevine leafroll-associated virus 3. [PDF]
Grapevine leafroll disease (GLD) is one of the most important grapevine viral diseases affecting grapevines worldwide. The impact on vine health, crop yield, and quality is difficult to assess due to a high number of variables, but significant economic ...
Adib eRowhani +14 more
core +2 more sources
Epidemiological characteristics of human-infective RNA viruses
RNA viruses are a major threat to human health. Here, based on extensive literature searches carried out over a period of 18 years, we provide a catalogue of all 214 known human-infective RNA virus species.
M. Woolhouse, Liam Brierley
semanticscholar +1 more source

