Results 111 to 120 of about 3,436,004 (333)

Transgenic resistance to PMTV and PVA provides novel insights to viral long-distance movement [PDF]

open access: yes, 2005
The studies in this thesis describe forms of transgenic resistance to plant viruses and how they can be used for studying viral infection cycle. S. tuberosum cv.
Germundsson, Anna
core  

Meta-transcriptomics and the evolutionary biology of RNA viruses

open access: yesVirus Research, 2017
Highlights • Meta-transcriptomics (bulk RNA-Seq) is a powerful new way to characterise viromes.• Meta-transcriptomic data are changing our understanding of virus evolution.• Invertebrates harbor an enormous phylogenetic and genomic diversity of RNA ...
M. Shi   +2 more
semanticscholar   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Mal de Río Cuarto Virus Infection Triggers the Production of Distinctive Viral-Derived siRNA Profiles in Wheat and Its Planthopper Vector

open access: yesFrontiers in Plant Science, 2017
Plant reoviruses are able to multiply in gramineae plants and delphacid vectors encountering different defense strategies with unique features. This study aims to comparatively assess alterations of small RNA (sRNA) populations in both hosts upon virus ...
Luis A. de Haro   +14 more
doaj   +1 more source

Sindbis virus ts103 has a mutation in glycoprotein E2 that leads to defective assembly of virions [PDF]

open access: yes, 1989
Sindbis virus mutant ts103 is aberrant in the assembly of virus particles. During virus budding, proper nucleocapsid-glycoprotein interactions fail to occur such that particles containing many nucleocapsids are formed, and the final yield of virus is low.
Hahn, Chang S.   +4 more
core  

Myxoma virus protein M029 is a dual function immunomodulator that inhibits PKR and also conscripts RHA/DHX9 to promote expanded host tropism and viral replication. [PDF]

open access: yes, 2013
Myxoma virus (MYXV)-encoded protein M029 is a member of the poxvirus E3 family of dsRNA-binding proteins that antagonize the cellular interferon signaling pathways.
Chan, Winnie M   +4 more
core   +1 more source

The diversity, evolution and origins of vertebrate RNA viruses

open access: yesCurrent Opinion in Virology, 2018
Highlights • A multitude of RNA viruses are present in lower vertebrates.• Fish harbor a remarkable array of RNA viruses.• RNA viruses in vertebrates generally follow the evolutionary history of their hosts.• Frequent cross-species transmission occurs on
Yong‐Zhen Zhang   +3 more
semanticscholar   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Grapevine leafroll-associated virus 3. [PDF]

open access: yes, 2013
Grapevine leafroll disease (GLD) is one of the most important grapevine viral diseases affecting grapevines worldwide. The impact on vine health, crop yield, and quality is difficult to assess due to a high number of variables, but significant economic ...
Adib eRowhani   +14 more
core   +2 more sources

Epidemiological characteristics of human-infective RNA viruses

open access: yesScientific Data, 2017
RNA viruses are a major threat to human health. Here, based on extensive literature searches carried out over a period of 18 years, we provide a catalogue of all 214 known human-infective RNA virus species.
M. Woolhouse, Liam Brierley
semanticscholar   +1 more source

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