Results 261 to 270 of about 3,202,245 (403)

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Synthesis and Bioevaluation of Chalcones as Broad-Spectrum Antiviral Compounds Against Single-Stranded RNA Viruses. [PDF]

Biomolecules
Kirton LKM, Yousef NN, Parks GD, Phanstiel O.   +3 more
europepmc   +1 more source

Systematic Analysis of Enhancer and Critical cis -Acting RNA Elements in the Protein-Encoding Region of the Hepatitis C Virus Genome [PDF]

, 2013
Derrick Chu, Songyang Ren, Stacy Hu, Wei Gang Wang, Aparna Subramanian, Deisy Contreras, Vidhya Kanagavel, Eric M. Chung, Justine S. Ko, Ranjit Singh Amirtham Jacob Appadorai, Sanjeev Sinha, Ziba Jalali, David Hardy, Samuel W. French, Vaithilingaraja Arumugaswami   +14 more
openalex   +1 more source

Rational Design of Optical Single‐Walled Carbon Nanotube‐Based Nanosensors with Biological Recognition Elements

Advanced Sensor Research, EarlyView.
This Review focuses on assessing and providing perspective on the field of rationally‐designed optical sensors constructed with single‐walled carbon nanotubes. The literature is reviewed and evaluated for SWCNT‐based sensors constructed with biomolecular recognition elements, including proteins, peptides, and oligonucleotides, as well as their methods ...
Amelia K. Ryan, Atara Israel, Maria Celina Stefoni, Catarina Ferraz, Ryan M. Williams   +4 more
wiley   +1 more source

Diversity and evolutionary history of RNA viruses among different horseshoe crab species. [PDF]

J Virol
Qi Y-H, Ye Z-X, Feng K-H, Ma X-W, Zhang C-X, Hu M-H, Shi M, Chen J-P, Li J-M.   +8 more
europepmc   +1 more source

Functional Significance of the Interaction of Hepatitis A Virus RNA with Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH): Opposing Effects of GAPDH and Polypyrimidine Tract Binding Protein on Internal Ribosome Entry Site Function

, 2000
MinKyung Yi, Derk E. Schultz, Stanley M. Lemon   +2 more
openalex   +2 more sources

Recognition of single-stranded RNA viruses by Toll-like receptor 7.

Proceedings of the National Academy of Sciences of the United States of America, 2004
Jennifer M. Lund, L. Alexopoulou, A. Sato, M. Karow, N. Adams, N. Gale, A. Iwasaki, R. Flavell   +7 more
semanticscholar   +1 more source

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

Advanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang, Qingwen Huang, Zhuo Chen, Weijian Meng, Hongliang Dong, Zhihong Qi, Liang Liu, Jie Shen, Daxing Xie   +8 more
wiley   +1 more source

Optimised Neutralisation Strategies for Validating the Virucidal Efficacy of Micro-Chem Plus™ Against High-Containment Negative-Sense RNA Viruses. [PDF]

Viruses
Gao X, Peng C, Shan C, Yao Y, Yuan Z.
europepmc   +1 more source

Potent and broad-spectrum cycloheptathiophene-3-carboxamide compounds that target the PA-PB1 interaction of influenza virus RNA polymerase and possess a high barrier to drug resistance

, 2019
Giulio Nannetti, Serena Massari, Beatrice Mercorelli, Chiara Bertagnin, Jenny Desantis, Giorgio Palù, Oriana Tabarrini, Arianna Loregian   +7 more
openalex   +2 more sources