Results 51 to 60 of about 3,202,245 (403)

A novel SARS-CoV-2 related coronavirus in bats from Cambodia

Nature Communications, 2021
In this study, Delaune et al., isolate and characterise a SARS-CoV-2-related coronavirus from two bats sampled in Cambodia. Their findings suggest that the geographic distribution of SARS-CoV-2-related viruses is wider than previously reported.
Deborah Delaune, Vibol Hul, Erik A. Karlsson, Alexandre Hassanin, Tey Putita Ou, Artem Baidaliuk, Fabiana Gámbaro, Matthieu Prot, Vuong Tan Tu, Sokha Chea, Lucy Keatts, Jonna Mazet, Christine K. Johnson, Philippe Buchy, Philippe Dussart, Tracey Goldstein, Etienne Simon-Lorière, Veasna Duong   +17 more
doaj   +1 more source

Early phylodynamics analysis of the COVID-19 epidemic in France

Peer Community Journal, 2021
France was one of the first countries to be reached by the COVID-19 pandemic. Here, we analyse 196 SARS-Cov-2 genomes collected between Jan 24 and Mar 24 2020, and perform a phylodynamics analysis.
Danesh, Gonché, Elie, Baptiste, Michalakis, Yannis, Sofonea, Mircea T, Bal, Antonin, Behillil, Sylvie, Destras, Grégory, Boutolleau, David, Burrel, Sonia, Marcelin, Anne-Geneviève, Plantier, Jean-Christophe, Thibault, Vincent, Simon-Loriere, Etienne, van der Werf, Sylvie, Lina, Bruno, Josset, Laurence, Enouf, Vincent, Alizon, Samuel   +17 more
doaj   +1 more source

Visualization of positive and negative sense viral RNA for probing the mechanism of direct-acting antivirals against hepatitis C virus [PDF]

, 2019
RNA viruses are highly successful pathogens and are the causative agents for many important diseases. To fully understand the replication of these viruses it is necessary to address the roles of both positive-strand RNA ((+)RNA) and negative-strand RNA ((
Bassit, Leda C, Huber, Andrew D, Ji, Juan, Lan, Shuiyun, Liu, Dandan, Michailidis, Eleftherios, Ndongwe, Tanyaradzwa P, Puray-Chavez, Maritza N, Ralston, Robert, Rice, Charles M, Saeed, Mohsan, Sarafianos, Stefan G, Schinazi, Raymond F, Tedbury, Philip R   +13 more
core   +2 more sources

A novel mechanism underlying the innate immune response induction upon viral-dependent replication of host cell mRNA: A mistake of +sRNA viruses' replicases [PDF]

, 2017
Viruses are lifeless particles designed for setting virus-host interactome assuring a new generation of virions for dissemination. This interactome generates a pressure on host organisms evolving mechanisms to neutralize viral infection, which places the
Colombo, Maria Isabel, Delgui, Laura Ruth   +1 more
core   +2 more sources

Translation of Plant RNA Viruses [PDF]

Viruses, 2021
Plant RNA viruses encode essential viral proteins that depend on the host translation machinery for their expression. However, genomic RNAs of most plant RNA viruses lack the classical characteristics of eukaryotic cellular mRNAs, such as mono-cistron, 5′ cap structure, and 3′ polyadenylation.
Guowei Geng, Deya Wang, Zhifei Liu, Yalan Wang, Mingjing Zhu, Xinran Cao, Chengming Yu, Xuefeng Yuan   +7 more
openaire   +3 more sources

The emerging SARS-CoV, MERS-CoV, and SARS-CoV-2: An insight into the viruses zoonotic aspects [PDF]

Veterinary World, 2021
Zoonotic coronavirus disease (COVID) has emerged in the past two decades and caused a pandemic that has produced a significant universal health alarm. Severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome-CoV (MERS-
Karima A. Al-Salihi, Jenan Mahmood Khalaf   +1 more
doaj   +1 more source

Metatranscriptomic reconstruction reveals RNA viruses with the potential to shape carbon cycling in soil

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance The diversity and ecology of RNA viruses is severely understudied in complex environments. Here we investigate the diversity and community patterns of soil RNA viruses by analyzing assembled metatranscriptomes.
Evan P. Starr, E. Nuccio, J. Pett‐Ridge, J. Banfield, M. Firestone   +4 more
semanticscholar   +1 more source

Efficient Protein Expression and Virus-Induced Gene Silencing in Plants Using a Crinivirus-Derived Vector. [PDF]

, 2018
Plant virus-based vectors are valuable tools for recombinant gene expression and functional genomics for both basic and applied research. In this study, Lettuce infectious yellows virus (LIYV) of the genus Crinivirus was engineered into a virus vector ...
Falk, Bryce W, Qiao, Wenjie
core   +7 more sources

RNA viruses and mutations

Uirusu, 2005
Actively replicating RNA viruses in nature are continually changing their genetic information by spontaneous mutations. These changes often result in alterations in immune-sensitivity, drug-sensitivity, cell-tropism, and host-range, causing uncontrollability of the pathogen and emerging/re-emerging infections. To better understand the virus changes and
Hironori, Sato, Masaru, Yokoyama
openaire   +3 more sources

Virus-derived DNA drives mosquito vector tolerance to arboviral infection

Nature Communications, 2016
Mosquitoes tolerate long-lasting viral infections, which makes them efficient vectors for human viral diseases. Here, the authors show that the tolerance of Aedesmosquitoes to infection with dengue or chikungunya viruses depends on the production of ...
Bertsy Goic, Kenneth A. Stapleford, Lionel Frangeul, Aurélien J. Doucet, Valérie Gausson, Hervé Blanc, Nidia Schemmel-Jofre, Gael Cristofari, Louis Lambrechts, Marco Vignuzzi, Maria-Carla Saleh   +10 more
doaj   +1 more source