Results 151 to 160 of about 836,536 (329)
A layperson encounter, on the "modified" RNA world. [PDF]
Proc Natl Acad Sci U S A, 2021 Pederson T.
europepmc +1 more source
Editorial: The Lesser Known World of RNA Polymerases
Frontiers in Molecular Biosciences, 2021 Olga Calvo +3 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Rolling Circles as a Means of Encoding Genes in the RNA World. [PDF]
Life (Basel), 2022 Rivera-Madrinan F, Di Iorio K, Higgs PG.
europepmc +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
The expanding world of small RNAs in plants
, 2015 Filipe Borges, Robert A. Martienssen
openalex +1 more source
Early Immunogenicity and Safety of the Third Dose of BNT162b2 Messenger RNA Coronavirus Disease 2019 Vaccine Among Adults Older Than 60 Years: Real-World Experience [PDF]
, 2021 Mayan Gilboa +16 more
openalex +1 more source
Small interfering RNA: potential in real-world clinical practice
Реальная клиническая практика: данные и доказательстваThis review describes the basics of protein biosynthesis and RNA interference processes, discusses the useful and unique properties of siRNA therapy, its advantages and disadvantages in comparison with other gene silencing methods, provides a brief ...
A. S. Motrinchuk, A. R. Kasimova
doaj +1 more source