Results 281 to 290 of about 836,536 (329)
Towards a Prebiotically Plausible Mechanism for the Emergence of RNA, Ribozymes and the RNA World
, 2015 Lyssa L. Martin
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Cellular and Molecular Life Sciences, 2006 The RNA world hypothesis states that life originated via a system based on RNA genomes and RNA catalysts. Researchers have been trying to develop such a system since catalytic RNAs (ribozymes) were discovered in 1982. This review summarizes the recent progress made in that endeavor and outlines the obstacles that remain to be overcome.
Ulrich F. Müller
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Trends in Biochemical Sciences, 1999
A popular theory of life's origins states that the first biocatalysts were not made of protein but were made of RNA or a very similar polymer. Experiments are beginning to confirm that the catalytic abilities of RNA are compatible with this 'RNA world' hypothesis. For example, RNA can synthesize short fragments of RNA in a template-directed fashion and
D P, Bartel, P J, Unrau
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A popular theory of life's origins states that the first biocatalysts were not made of protein but were made of RNA or a very similar polymer. Experiments are beginning to confirm that the catalytic abilities of RNA are compatible with this 'RNA world' hypothesis. For example, RNA can synthesize short fragments of RNA in a template-directed fashion and
D P, Bartel, P J, Unrau
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From RNA world to RNA-peptide world: A review
Theoretical and Natural Science, 2023How life starts from small molecules to RNAs and further to modern life is an unanswered question. Cyanosulfitic chemistry established the synthesis of building blocks, including 12 proteinogenic amino acids, 4 ribo- and deoxyribo-nucleosides, and phospholipids, from hydrogen cyanide and hydrogen sulfite under prebiotically plausible conditions.
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New England Journal of Medicine, 2018
RNA Biology and Parity at the Bench The 2018 Lasker–Koshland Special Achievement Award in Medical Science, announced September 11, goes to Joan A. Steitz for her pioneering discoveries in RNA biology and her work toward better representation of women and minorities in scientific research.
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RNA Biology and Parity at the Bench The 2018 Lasker–Koshland Special Achievement Award in Medical Science, announced September 11, goes to Joan A. Steitz for her pioneering discoveries in RNA biology and her work toward better representation of women and minorities in scientific research.
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Journal of Chemical Education, 2010
This puzzle contains 33 names, abbreviations, and acronyms that describe the implications of the RNA World Hypothesis in a 13-by-14-letter matrix. A descriptive narrative with underlined spaces to be filled gives clues to the terms students need to find.
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This puzzle contains 33 names, abbreviations, and acronyms that describe the implications of the RNA World Hypothesis in a 13-by-14-letter matrix. A descriptive narrative with underlined spaces to be filled gives clues to the terms students need to find.
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Paleontological Journal, 2010
Based on the modern concept of multiplicity of RNA functions, certain new mechanisms, which could have played a key role in the origin and evolution of the ancient RNA world, are discussed. In particular, the reaction of spontaneous transesterification of polyribonucleotides, which was discovered by A.B.
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Based on the modern concept of multiplicity of RNA functions, certain new mechanisms, which could have played a key role in the origin and evolution of the ancient RNA world, are discussed. In particular, the reaction of spontaneous transesterification of polyribonucleotides, which was discovered by A.B.
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RNA editing: World's smallest introns?
Cell, 1991Thomas R. Cech Department of Chemistry and Biochemistry Howard Hughes Medical Institute University of Colorado Boulder, Colorado 80309-0215 It once seemed that the nucleotide sequence of every mRNA would be a simple copy of the sequence of its DNA template.
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