Results 161 to 170 of about 267,874 (284)

Synthetic polymer nanocarrier enhances dsRNA stability but not RNAi efficacy in Brassicogethes aeneus

open access: yesPest Management Science, EarlyView.
Experimental setup for dsRNA feeding in Brassicogethes aeneus to evaluate the effect of a synthetic polymer nanocarrier on RNAi efficiency. The experiment assessed whether the nanocarrier enhances RNAi after oral dsRNA delivery. (a) Stability of dsRNA–nanocarrier complexes was tested in simulated gut conditions. (b) Gene expression of αCOP and dre4 was
Triin Kallavus   +13 more
wiley   +1 more source

Gene‐specific double‐stranded RNAs induce mortality in the South African mealybug Delottococcus aberiae

open access: yesPest Management Science, EarlyView.
Gene‐specific double‐stranded RNAs effectively silence essential genes in the invasive citrus pest Delottococcus aberiae, leading to significant mortality through both microinjection and oral delivery. These results provide proof of concept for RNA interference‐based biopesticides as selective and sustainable tools for citrus integrated pest management.
Carolina Gallego‐Giraldo   +6 more
wiley   +1 more source

ROS-Responsive Biomimetic Nanocomplexes of Liposomes and Macrophage-Derived Exosomes for Combination Breast Cancer Therapy

open access: yesInternational Journal of Nanomedicine
Minhao Xu,1,* Lu Bai,1,* Meng Sun,1 Xinlei Yan,1 Ying Xiong,2 Yu Wang,1 Yue Guo,1 Xingyou Liu,1 Leijie Yu,1 Xing Zhong,1 Mengqiong Ran,1 Ben Wang,3 Yaqin Tang,1 Robert J Lee,4 Jing Xie1 1School of Pharmacy and Bioengineering, Chongqing University
Xu M   +14 more
doaj  

Thirty years of glyphosate‐resistant crops and weeds: Current situation and future prospects

open access: yesPest Management Science, EarlyView.
Since 1996, when the first glyphosate‐resistant crop was commercialized and the first resistant weed was reported, resistance has expanded globally. This review analyzes emergence patterns across weed species, crops, regions, resistance mechanisms, and herbicides.
Ricardo Alcántara‐de la Cruz   +7 more
wiley   +1 more source

Pedunculoside Inhibits Hepatocellular Carcinoma Progression by Activating the MAPK Signaling Pathway Through Targeting and Suppressing CDK4

open access: yesPhytotherapy Research, EarlyView.
Pedunculoside targets and suppresses CDK4; consequently, it activates the MAPK pathway and inhibits hepatocellular carcinoma progression. ABSTRACT Hepatocellular carcinoma (HCC) remains a major challenge in cancer prevention and treatment, highlighting the urgent need for effective and low‐toxicity anti‐HCC therapies. Recently, CDK4‐targeted inhibitors
Yang Zhou   +9 more
wiley   +1 more source

Pathogen Response Genes Mediate Caenorhabditis elegans Innate Immunity

open access: yes, 2012
Innate immunity is crucial in the response and defense against pathogens for invertebrates and vertebrates alike. The soil nematode Caenorhabditis elegans is a useful model to study the eukaryotic innate immune response to microbial pathogenesis.
Anthony, Hannah L.
core  

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