Results 171 to 180 of about 195,676 (344)

Comparative Satellitomics in Arowanas (Telostei, Osteoglossiformes) Sheds Light on the Evolution of Ancient Satellite DNAs

open access: yesIntegrative Zoology, EarlyView.
This work focused on arowana fishes (Teleostei, Osteoglossiformes) as a model; their widespread intercontinental distribution and basal phylogenetic position within Teleostei make them a compelling model for evolutionary research, especially in the realm of satDNA molecular evolution. Through the integration of genomic and chromosomal data, we analyzed
Fernando Henrique Santos de Souza   +9 more
wiley   +1 more source

RNAi-mediated oncogene silencing confers resistance to crown gall tumorigenesis

open access: green, 2001
Matthew A. Escobar   +3 more
openalex   +1 more source

CRISPR vs. nematodes: A new era of genetic solutions for potato crop protection

open access: yesAnnals of Applied Biology, EarlyView.
This review highlights the impact of nematodes on potato production and explores CRISPR/Cas genome editing as a breakthrough strategy for enhancing resistance. We discuss the potential, challenges, and future directions of CRISPR‐based approaches in developing resilient potato cultivars.
Karam Mostafa   +6 more
wiley   +1 more source

dVGLUT Is a Mediator of Sex Differences in Dopamine Neuron Mitochondrial Function Across Aging and in a Parkinson's Disease Model

open access: yesAging Cell, EarlyView.
We examined sex and regional differences in mitochondrial reactive oxygen species (ROS) generation and their implications for dopamine (DA) neuron resilience using the Drosophila model. We found: (1) higher basal ROS in males versus females; (2) age‐related ROS increases in both sexes; and (3) DA neuron‐specific dVGLUT RNAi knockdown raised ROS in ...
Silas A. Buck   +7 more
wiley   +1 more source

Metformin and Dietary Restriction Counteract Aging via Reducing m6A–Dependent Stabilization of Methionine Synthase mRNA in Brachionus asplanchnoidis (Rotifera)

open access: yesAging Cell, EarlyView.
Metformin and dietary restriction modulate m6A to extend lifespan of rotifer, highlighting MTR as a central regulator of aging through methionine metabolism. ABSTRACT Metformin, a medication primarily used to treat diabetes, has gained attentions for its potential antiaging properties.
Yu Zhang   +8 more
wiley   +1 more source

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