Results 351 to 360 of about 330,568 (380)
Some of the next articles are maybe not open access.
RNAi-based therapeutics and tumor targeted delivery in cancer.
Advanced Drug Delivery Reviews, 2022Goknur Kara, G. Calin, B. Ozpolat
semanticscholar +1 more source
Science, 2003
Genes are silenced when tiny regulatory RNAs bind to target messenger RNAs. But it is becoming clear that RNA interference goes beyond these interactions. In their perspective, [Matzke and Matzke][1] discuss recent work ([Schramke and Allshire][2]) that shows that the silencing pathway can induce heterochromatin formation in DNA that is normally ...
Marjori, Matzke, Antonius J M, Matzke
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Genes are silenced when tiny regulatory RNAs bind to target messenger RNAs. But it is becoming clear that RNA interference goes beyond these interactions. In their perspective, [Matzke and Matzke][1] discuss recent work ([Schramke and Allshire][2]) that shows that the silencing pathway can induce heterochromatin formation in DNA that is normally ...
Marjori, Matzke, Antonius J M, Matzke
openaire +2 more sources
2011
Engineered "computing" biological networks are a generalization of endogenous regulatory pathways. They are intended to generate novel biological responses based on preprogrammed processing of multiple molecular signals. We have recently introduced an approach to constructing complex signal processing networks in mammalian cells using RNA interference (
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Engineered "computing" biological networks are a generalization of endogenous regulatory pathways. They are intended to generate novel biological responses based on preprogrammed processing of multiple molecular signals. We have recently introduced an approach to constructing complex signal processing networks in mammalian cells using RNA interference (
openaire +2 more sources
A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila
Nature, 2007G. Dietzl +13 more
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Argonaute2 Is the Catalytic Engine of Mammalian RNAi
Science, 2004Jidong Liu +9 more
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The current state and future directions of RNAi-based therapeutics
Nature reviews. Drug discovery, 2019Ryan L Setten, J. Rossi, Si-ping Han
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Current Protocols in Bioinformatics, 2004
AbstractRNAi is a novel genetic tool that is poised to revolutionize the study of genetics and gene networks. Use of this tool requires knowledge of the underlying mechanisms and application of this knowledge to the construction of a gene‐silencing library. This unit discusses approaches to rational design of this library and its use in experiments. It
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AbstractRNAi is a novel genetic tool that is poised to revolutionize the study of genetics and gene networks. Use of this tool requires knowledge of the underlying mechanisms and application of this knowledge to the construction of a gene‐silencing library. This unit discusses approaches to rational design of this library and its use in experiments. It
openaire +2 more sources
Clay nanosheets for topical delivery of RNAi for sustained protection against plant viruses
Nature Plants, 2017N. Mitter +10 more
semanticscholar +1 more source