Results 41 to 50 of about 269,285 (308)

A robust in-vitro and ex-vitro Agrobacterium rhizogenes-mediated hairy root transformation system in mungbean for efficient visual screening of transformants using the RUBY reporter

open access: yesBMC Plant Biology
Background Mungbean is one of the most economically important grain legume crops in Asia. Functional genomics studies in mungbean are necessary to understand the molecular mechanisms behind agronomic traits, to advance the crop improvement. However, this
Sanjeev Kumar   +3 more
doaj   +1 more source

When an Intruder Comes Home: GM and GE Strategies to Combat Virus Infection in Plants

open access: yesAgriculture
Viruses are silent enemies that intrude and take control of the plant cell’s machinery for their own multiplication. Infection by viruses and the resulting damage is still a major challenge in the agriculture sector.
Adeeb Rahman, Neeti Sanan-Mishra
doaj   +1 more source

Exit from Pluripotency Assay of Mouse Embryonic Stem Cells

open access: yesBio-Protocol, 2017
A novel method to assess the dissolution of the core pluripotency transcription-factor circuit of mouse Embryonic Stem Cells (mESCs) has been developed (Ying et al., 2003; Betschinger et al., 2013).
Daniel Cirera-Salinas, Constance Ciaudo
doaj   +1 more source

Effects of introduction of sorghum RbcS with rice RbcS knockdown by RNAi on photosynthetic activity and dry weight in rice

open access: yesPlant Production Science, 2021
Rubisco is the key enzyme responsible for photosynthetic CO2 fixation. Previously, we succeeded to increase the catalytic rate (kcat) of Rubisco by the overexpression of sorghum C4-type Rubisco small subunit (RbcS) in rice. These Rubisco are present as a
Kazuma Sakoda   +5 more
doaj   +1 more source

Effects of Nanoparticles on Double-Stranded RNA Stability in Moth Hemolymph [PDF]

open access: yes, 2018
RNA interference (RNAi) is an immune response in which double-stranded RNA (dsRNA) suppresses a target gene. By designing dsRNA to target genes that are necessary for life, dsRNA can potentially be used as an insecticide.
Cooper, Anastasia   +7 more
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

ARMOUR – A Rice miRNA: mRNA Interaction Resource

open access: yesFrontiers in Plant Science, 2018
ARMOUR was developed as ARice miRNA:mRNA interaction resource. This informative and interactive database includes the experimentally validated expression profiles of miRNAs under different developmental and abiotic stress conditions across seven Indian ...
Neeti Sanan-Mishra   +5 more
doaj   +1 more source

Suppression of Argonaute 2 Transcript Levels in Du182A Cells [PDF]

open access: yes, 2018
RNA interference (RNAi) uses double-stranded RNA (dsRNA) molecules to degrade and suppress the transcript level of a complementary mRNA target1.
Featherston, Kyah   +2 more
core  

Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy. [PDF]

open access: yes, 2017
Transverse (T)-tubules make-up a specialized network of tubulated muscle cell membranes involved in excitation-contraction coupling for power of contraction. Little is known about how T-tubules maintain highly organized structures and contacts throughout
Fujita, Naonobu   +10 more
core   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

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