Results 21 to 30 of about 207,765 (300)
Molecular Therapy, 2011 A recurring theme in the way that many pharmaceutical companies approach new technologies is that they are initially extremely enthusiastic, perhaps excessively so, but then subsequently overreact in the opposite direction, abandoning them when the first bumps in the road come along.
openaire +2 more sources
RNA interference, growth and differentiation appear normal in African trypanosomes lacking Tudor staphylococcal nuclease. [PDF]
, 2010 Ribonucleases play important roles in the RNA interference (RNAi) pathway. The Dicer endonuclease converts double-stranded (ds)RNA into small interfering (si)RNA and the Slicer endonuclease, as a component of the RNA induced silencing complex (RISC ...
Louise E. Kemp +9 more
core +1 more source
Developmental Cell, 2005 Processing bodies (P bodies) are discrete cytoplasmic foci to which mRNA is routed for degradation. In mammalian cells, they are also associated with miRNA-induced translational silencing and siRNA-induced mRNA degradation. In a recent issue of Molecular Cell, Ding and coworkers described an argonaute-interacting protein that appears to promote the ...
openaire +2 more sources
Investigation of RNA-induced gene silencing in the fission yeast Schizosaccharomyces pombe [PDF]
, 2007 PhDRNA interference (RNAi) is a gene regulating system to which can silence genes at both transcriptional and post-transcriptional levels. In this thesis, a ura4-based RNAi selective assay was developed in the fission yeast Schizosaccharomyces pombe ...
Wang, Huan
core +2 more sources
RNAi-Mediated Silencing of ITPK Gene Reduces Phytic Acid Content
, 2019 Revision of RNAi-Mediated Silencing of ITPK Gene Reduces Phytic Acid ...
Swapan Datta (7021088)
core +2 more sources
Argonaute 2 Is Required for Extra-embryonic Endoderm Differentiation of Mouse Embryonic Stem Cells
Stem Cell Reports, 2018 Summary: In mouse, although four Argonaute (AGO) proteins with partly overlapping functions in small-RNA pathways exist, only Ago2 deficiency causes embryonic lethality.
Richard Patryk Ngondo +10 more
doaj +1 more source
Exit from Pluripotency Assay of Mouse Embryonic Stem Cells
Bio-Protocol, 2017 A novel method to assess the dissolution of the core pluripotency transcription-factor circuit of mouse Embryonic Stem Cells (mESCs) has been developed (Ying et al., 2003; Betschinger et al., 2013).
Daniel Cirera-Salinas, Constance Ciaudo
doaj +1 more source
RNA interference is ineffective as a routine method for gene silencing in chick embryos as monitored by fgf8 silencing. [PDF]
, 2013 The in vivo accessibility of the chick embryo makes it a favoured model system for experimental developmental biology. Although the range of available techniques now extends to miss-expression of genes through in ovo electroporation, it remains difficult
Bueno i Torrens, David, 1965- +1 more
core +5 more sources
ARMOUR – A Rice miRNA: mRNA Interaction Resource
Frontiers in Plant Science, 2018 ARMOUR was developed as ARice miRNA:mRNA interaction resource. This informative and interactive database includes the experimentally validated expression profiles of miRNAs under different developmental and abiotic stress conditions across seven Indian ...
Neeti Sanan-Mishra +5 more
doaj +1 more source
Figure 5 - DN SERCA and MLCK-RNAi
, 2022 Datasets of continuous heatshock of w; tub67-GAL4,tub15-GAL4 / UAS-MLCK-RNAi and w; Mef2-GAL4/UAS-SERCA.R751Q (temperature sensative dominant negative SERCA) embryos. Each embryo is scored according to how many constrictions form.
Noah Mitchell (12456507)
core +1 more source