Results 71 to 80 of about 207,765 (300)

An introduction to PIWI-interacting RNAs (piRNAs) in the context of metazoan small RNA silencing pathways

open access: yesRNA Biology, 2022
PIWI proteins and their associated PIWI-interacting RNAs (piRNAs) constitute a small RNA-based adaptive immune system that restricts the deleterious activity of mobile genetic elements to protect genome integrity.
Astrid D. Haase
doaj   +1 more source

The Many Faces of RNAi [PDF]

open access: yesDevelopmental Cell, 2011
Small non-coding RNAs, through association with Argonaute protein family members, have a variety of functions during the development of an organism. Although there is increased mechanistic understanding of the RNA interference (RNAi) pathways surrounding these small RNAs, how their effects are modulated by subcellular compartmentalization and cross ...
openaire   +4 more sources

RNAi in Budding Yeast [PDF]

open access: yesScience, 2009
Yeast Joins RNAi Club RNA interference (RNAi) silences gene expression via small interfering (si) RNAs that bind to target sequences. RNAi has been found in almost all eukaryotes examined, with the notable exception of the budding yeast, Saccharomyces cerevisiae , one of the
Drinnenberg, Ines A.   +6 more
openaire   +4 more sources

RNAi in the Rhizarian Phytopathogen Plasmodiophora brassicae: The Causal Agent of Clubroot Disease in Cruciferous Crops

open access: yesAdvanced Science, EarlyView.
This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang   +13 more
wiley   +1 more source

Identification, Expression and Function of Heat Shock Transcription Factor (HSF-1) Gene in Exopalaemon carinicauda Under High Temperature Stress [PDF]

open access: yesProgress in Fishery Sciences
Exopalaemon carinicauda, a shrimp Litopenaeus vannamei species endemic to China, holds significant economic value due to its desirable meat quality, high protein content, and low fat levels, making it a popular choice among consumers.
XIA Jinqi   +7 more
doaj   +1 more source

The ABCB Multidrug Resistance Proteins Do Not Contribute to Ivermectin Detoxification in the Colorado Potato Beetle, Leptinotarsa decemlineata (Say)

open access: yesInsects, 2020
The Colorado potato beetle, Leptinotarsa decemlineata (Say), is a significant agricultural pest that has developed resistance to many insecticides that are used to control it.
Grant Favell   +2 more
doaj   +1 more source

Small regulatory RNAs: from bench to bedside – a keystone symposia meeting report

open access: yesRNA Biology, 2023
The Keystone Symposium ‘Small Regulatory RNAs: From Bench to Bedside’ was held in Santa Fe, New Mexico from May 1–4, 2022. The symposium was organized by Frank J. Slack, Jörg Vogel, Ivan Martinez and Karyn Schmidt, and brought together scientists working
Soo Mi Lee   +3 more
doaj   +1 more source

RNAi-mediated resistance to SMV and BYMV in transgenic tobacco

open access: yes, 2016
Soybean mosaic virus (SMV) and bean yellow mosaic virus (BYMV) are two typical types of viruses that cause mosaic in soybean plants. Multiple viral infections at the same site can lead to 66% to 80% yield reduction.
Lo Thi Mai Thu (12845396)   +5 more
core   +1 more source

Concerted Action of Targeted Nucleic Acid Therapeutics as Flexible, Precision and Personalized Cancer Treatment

open access: yesAdvanced Science, EarlyView.
Combinations of small activating RNAs and small interfering RNAs were developed as personalized precision therapies that simultaneously activate tumor suppressors and silence oncogenes according to the molecular signatures of patient tumors. This combination strategy demonstrated superior anticancer efficacy, highlighting the promise of precision ...
Jing Wu   +18 more
wiley   +1 more source

RNAi-mediated knockdown of daf-12 in the model parasitic nematode Strongyloides ratti

open access: yes, 2019
The gene daf-12 has long shown to be involved in the dauer pathway in Caenorhabditis elegans (C. elegans). Due to the similarities of the dauer larvae of C. elegans and infective larvae of certain parasitic nematodes such as Strongyloides spp., this gene
Alex Dulovic (6528617)   +1 more
core   +1 more source

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