Results 101 to 110 of about 20,593,893 (291)
A. Indicated concentrations of magnesium and ammonium ions were used to assay the pre-tRNA cleavage by RNase P RNA and RNase P-G protein. The reactions contained 50 nM of RNase P RNA and 100 nM of RNase P-G protein. B.
Shah Ubaid-ullah (487293) +3 more
core +1 more source
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira +8 more
wiley +1 more source
Introduction. RNase MRP/RNase P systems - [PDF]
Contains fulltext : 29698___.PDF (Publisher’s version ) (Open Access)
Karwan, R., Pluk, H., Venrooij, W.J. van
openaire
Varieties of RNase P: A nomenclature problem?
Twenty-five years ago, a basic tenet of biochemistry held that enzymes are made solely of protein. Ribosomes, which are large ribonucleoprotein enzymes, were conveniently overlooked (but see Woese, 1967; Crick, 1968; Orgel, 1968). The then current orthodoxy was first challenged by the discovery that Escherichia coli RNase P had an essential RNA subunit
S, Altman, V, Gopalan, A, Vioque
openaire +3 more sources
Distribution of ribonucleoprotein and protein-only RNase P in Eukarya
RNase P is the endonuclease that removes 5' leader sequences from tRNA precursors. In Eukarya, separate RNase P activities exist in the nucleus and mitochondria/plastids.
Giege, P. (Philippe) +6 more
core +1 more source
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song +14 more
wiley +1 more source
Background The ribonuclease H (RNase H) domains of retroviral reverse transcriptases play an essential role in the replication cycle of retroviruses. During reverse transcription of the viral genomic RNA, an RNA/DNA hybrid is created whose RNA strand ...
Leo Berit +4 more
doaj +1 more source
Navigating Lipid Nanostructure Design Space Through Continuous Microfluidic Automation
LipidXplorer is a novel microfluidic platform which enables rapid navigation of lipid particle design space for high‐resolution phase mapping, lipid nanoparticle optimization, membrane biophysics, and functional nanomaterial discovery. It combines programmable composition control, continuous nanoparticle formation, and automated well‐plate collection ...
Bradley Diggines +10 more
wiley +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
A tRNA-modifying enzyme facilitates RNase P activity in Arabidopsis nuclei.
RNase P is the essential activity that performs the 5' maturation of transfer RNA (tRNA) precursors. Beyond the ancestral form of RNase P containing a ribozyme, protein-only RNase P enzymes termed PRORP were identified in eukaryotes.
Giegé, P. +11 more
core +1 more source

