Results 131 to 140 of about 430,076 (284)
Modulation of ppp(A2'p)nA-dependent RNase by a temperature-sensitive mutant of vaccinia virus [PDF]
, 1989 Randall J. Cohrs +4 more
openalex +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
Partial characterization of an RNA component that copurifies with Saccharomyces cerevisiae RNase P. [PDF]
, 1989 J Y Lee, David R. Engelke
openalex +1 more source
RNase MRP/RNase P: a structure‐function relation conserved in evolution? [PDF]
FEBS Letters, 1993 RNase P and RNase MRP are related ribonucleoproteins. RNase MRP processes mitochondrial precursor‐ (primer) RNAs, whereas RNase P cleaves precursor‐tRNAs to produce their mature 5'‐ends. Both RNase P and RNase MRP are associated with the Th/To ribonucleoprotein suggesting possible interrelated pathways and/or functions.
openaire +3 more sources
Advanced Healthcare Materials, EarlyView.A flexible electrode loaded with a carbon nanowire network (CC@C‐NWN) is developed for electrochemically generating reactive chlorine species (RCS) from abundant chloride ions in body fluids for tumor therapy. CC@C‐NWN enhances chlorine evolution, inducing redox dysregulation and synergistic apoptosis‐ferroptosis in tumor cells.
Cuinan Jiang +10 more
wiley +1 more source
Ribonuclease (RNase) Prolongs Survival of Grafts in Experimental Heart Transplantation
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016 BackgroundCell damage, tissue and vascular injury are associated with the exposure and release of intracellular components such as RNA, which promote inflammatory reactions and thrombosis. Based on the counteracting anti‐inflammatory and cardioprotective
Eike Kleinert +15 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Through tuning biomimetic scaffold stiffness and matrix composition the reparative capacity of astrocyte progenitors is enhanced. Soft, collagen‐IV/fibronectin‐functionalized scaffolds promote progenitor growth while improving angiogenic, immunomodulatory, and neurotrophic capacity in a stiffness and matrix‐dependent manner, demonstrating the impact of
Cian O'Connor +10 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Hybrid NPs are developed as efficient, scalable nanocarriers for in vitro microRNA delivery, ensuring high loading efficiency, controlled release, physiological and long‐term storage stability. They outperform commercial lipid‐based reagents in terms of transfection efficiency and biocompatibility.
Letizia Nicoletti +11 more
wiley +1 more source
Advanced Materials Interfaces, EarlyView.This study investigates the impact of nanostructured surface modification on corrosion resistance, HUVEC functions, and platelet interactions of 316L SS for cardiovascular stents. Nanostructured surfaces enhanced HUVEC proliferation, migration, and angiogenesis‐related gene expression while reducing platelet adhesion and hemolysis.
Yasar Kemal Erdogan +2 more
wiley +1 more source
An immunological determinant of RNase P protein is conserved between Escherichia coli and humans. [PDF]
, 1989 Mark J. Mamula +3 more
openalex +1 more source