Results 191 to 200 of about 436,820 (281)

Genomic and Cis‐Regulatory Basis of a Plastic C3‐C4 Photosynthesis in Eleocharis Baldwinii

Advanced Science, EarlyView.
The sedge Eleocharis baldwinii remarkably switches between C3‐like and C4‐like photosynthesis in response to environmental conditions. Combining gap‐free genome assembly with single‐cell multi‐omics, this study uncovers how subgenome dominance and cell‐specific cis‐regulation enable C4 photosynthesis.
Lu Chen, Yanfeng Jia, Zaihui Zhou, Qiying Jiang, Jianlin Liu, Jianhui Gu, Chuan Chen, Shujing Cheng, Jinfang Chu, Xin Liu, Yongjun Lin, Xiang Li   +11 more
wiley   +1 more source

Inactivation of RNase P in Escherichia coli significantly changes post-transcriptional RNA metabolism. [PDF]

Mol Microbiol, 2022
Mohanty BK, Kushner SR.
europepmc   +1 more source

POLE Deficiency Exacerbates Diesel Engine Exhaust‐Induced Genomic Instability and Malignant Transformation of Bronchial Epithelial Cells

Advanced Science, EarlyView.
This study establishes a diesel engine exhaust (DEE)‐induced malignant transformation model in bronchial epithelial cells. Whole genome sequencing（WGS） and RNA‐seq reveal DEE‐induced mutational signatures and gene expression profiles. Mechanistically, DEEaffect polymerase epsilon (POLE) and mismatch repair, driving genomic instability and promoting ...
Pimei Zhang, Zhaoxu Wu, Qiang Ju, Nuo Xu, Xian Chen, Hongguang Chen, Shuaishuai Yang, Jing Ji, Yanjie Zhao   +8 more
wiley   +1 more source

Reduction of <i>Drosophila</i> Mitochondrial RNase P in Skeletal and Heart Muscle Causes Muscle Degeneration, Cardiomyopathy, and Heart Arrhythmia. [PDF]

Front Cell Dev Biol, 2022
Saoji M, Petersen CE, Sen A, Tripoli BA, Smyth JT, Cox RT.   +5 more
europepmc   +1 more source

New insight into RNase P RNA structure from comparative analysis of the archaeal RNA [PDF]

, 2001
J. Kirk Harris, E. S. Haas, Daniel J. Williams, Daniel N. Frank, James W. Brown   +4 more
openalex   +1 more source

Localized Delivery of the mRNAs Encoding CD47 Inhibitor and Interleukins 12, 15, and 21 Elicits Robust Antitumor Immunity

Advanced Science, EarlyView.
The co‐delivery of mRNAs encoding a CD47 inhibitor and a cytokine cocktail (interleukins 12, 15, and 21) via lipid nanoparticles enables effective localized immunotherapy. This strategy not only suppresses tumor progression but also enhances type 1 conventional dendritic cell (cDC1) differentiation and activates CD8+ T cells, thereby inducing robust ...
Tao Jiang, Shuaiyang Jing, Haojun Li, Bao Xiao, Jiahui Jin, Xiu Sun, Juan Wang, Jing Liang, Tongze Cai, Huili Hu, Meilan Wei, Xuanrui Zhong, Yang Ji, Peng George Wang, Jianlong Zhou   +14 more
wiley   +1 more source

Protein–protein interactions with subunits of human nuclear RNase P [PDF]

, 2001
Taijiao Jiang, Sidney Altman
openalex   +1 more source

Discovery of Natural Compound α‐Hederin via Large‐Scale Screening as a Targeted JAK/STAT3 Inhibitor for Ovarian Cancer Therapy

Advanced Science, EarlyView.
This study identifies α‐Hederin as a potent dual JAK1/JAK2 inhibitor that blocks STAT3 activation in ovarian cancer. By disrupting STAT3‐driven transcriptional programs, α‐Hederin suppresses tumor proliferation, invasion, and EMT, while enhancing cisplatin efficacy and overcoming chemoresistance.
Jiayu Wang, Pengzhan He, Cheng Liu, Xin Chen, Yilin Tan, Rui Qu, Yan Zhang, Zhou Li, Tailang Yin, Zhinang Yin   +9 more
wiley   +1 more source

The conformational space of RNase P RNA in solution. [PDF]

Nature
Lee YT, Degenhardt MFS, Skeparnias I, Degenhardt HF, Bhandari YR, Yu P, Stagno JR, Fan L, Zhang J, Wang YX.   +9 more
europepmc   +1 more source

Ligand-dependent tRNA processing by a rationally designed RNase P riboswitch. [PDF]

Nucleic Acids Res, 2021
Ender A, Etzel M, Hammer S, Findeiß S, Stadler P, Mörl M.   +5 more
europepmc   +1 more source