Results 191 to 200 of about 25,923,055 (288)

Bacterial/archaeal protein-only RNase P: complementation in <i>Escherichia coli</i> uncovers coevolution of protein-only RNase P and precursor tRNA structures in <i>Aquifex aeolicus</i>. [PDF]

RNA
Davydov S, Wäber NB, Gößringer M, Klemm P, Rennar I, Lechner M, Hartmann RK.   +6 more
europepmc   +1 more source

The many faces of RNA-based RNase P, an RNA-world relic. [PDF]

Trends Biochem Sci, 2021
Phan HD, Lai LB, Zahurancik WJ, Gopalan V.   +3 more
europepmc   +1 more source

Self‐Assembling Peptide‐Adjuvant Conjugate (SaPAC) Platform for Precision Cancer Immunotherapy

Advanced Science, EarlyView.
A self‐assembling peptide–adjuvant conjugate links neoantigens to TLR7 agonism, forming cationic nanoparticles that enhance lymph‐node retention, dendritic‐cell activation, and antitumor T‐cell immunity. This chemically defined platform shows how synchronized antigen and innate stimulation can be adapted across melanoma, bladder cancer, and triple ...
Yang‐Fan Wu, Jing‐Chu Hu, Ye‐Fan Hu, Wen‐Jun Li, Li Rong, Ren‐Hao Li, Yuan Yao, Lehan Hu, Xiao‐Lei Wang, Bao‐Zhong Zhang, Yicheng Lu, Shing‐Fung Chow, Canhui Su, Thomas Yau, Clive Yik‐Sham Chung, Jian‐Dong Huang   +15 more
wiley   +1 more source

Structural basis of transfer RNA processing by bacterial minimal RNase P. [PDF]

Nat Commun
Teramoto T, Koyasu T, Yokogawa T, Adachi N, Mayanagi K, Nakamura T, Senda T, Kakuta Y.   +7 more
europepmc   +1 more source

Crystal structures and insights into precursor tRNA 5'-end processing by prokaryotic minimal protein-only RNase P. [PDF]

Nat Commun, 2022
Li Y, Su S, Gao Y, Lu G, Liu H, Chen X, Shao Z, Zhang Y, Shao Q, Zhao X, Yang J, Cao C, Lin J, Ma J, Gan J.   +14 more
europepmc   +1 more source

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

Advanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo, Joe G. Rizk, Emilia Calvano, Rajesh Sahu, Emina Colovic, Imane Chabba, Valentine Gilbart, Erwan Grandgirard, Bastien Morlet, Qingshuang Cai, Daniel Metzger, Delphine Duteil   +11 more
wiley   +1 more source

The conformational space of RNase P RNA in solution. [PDF]

Nature
Lee YT, Degenhardt MFS, Skeparnias I, Degenhardt HF, Bhandari YR, Yu P, Stagno JR, Fan L, Zhang J, Wang YX.   +9 more
europepmc   +1 more source

Inactivation of RNase P in Escherichia coli significantly changes post-transcriptional RNA metabolism. [PDF]

Mol Microbiol, 2022
Mohanty BK, Kushner SR.
europepmc   +1 more source

Proteinaceous RNase P

, 2013
Ribonuklease P (RNase P) ist eine Endonuklease, die die 5´ Flanke von pre-tRNAs entfernt und somit essentiell für die Funktion von tRNAs in der Proteinsynthese ist.
Weber, Christoph
core  

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

Advanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi, Qiang Zhao, Yue Lve, Yaming Yuan, Tingting Zhou, Yue Yuan, Dexi Wu, Yifan Tang, Yan Liu, Zhigang Li, Chunping Jiang, Qiurong Ding   +11 more
wiley   +1 more source