The rice RNase P protein subunit Rpp30 confers broad-spectrum resistance to fungal and bacterial pathogens. [PDF]
Li W+9 more
europepmc +1 more source
Conditional Expression of RNase P in the CyanobacteriumSynechocystis sp. PCC6803 Allows Detection of Precursor RNAs [PDF]
Cristina Tous+2 more
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Cytokine Storm Induction Linked to Multi‐Organ Failure in Fatal Jellyfish Stings
N. nomurai is the most important injurious species in the coastal area of China. Model construction, omics analysis, mechanism exploration, and intervention measures of N. nomurai envenomation are performed in the current study, and it suggested that cytokine storm played an important role in pathogenesis.
Yichao Wang+15 more
wiley +1 more source
Use of a small molecule microarray screen to identify inhibitors of the catalytic RNA subunit of Methanobrevibacter smithii RNase P. [PDF]
Sidharthan V+8 more
europepmc +1 more source
Surveillance of RNase P, PMMoV, and CrAssphage in wastewater as indicators of human fecal concentration across urban sewer neighborhoods, Kentucky. [PDF]
Holm RH+9 more
europepmc +1 more source
Effective inhibition of herpes simplex virus 1 gene expression and growth by engineered RNase P ribozyme [PDF]
Phong Trang
openalex +1 more source
The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang+15 more
wiley +1 more source
The discovery of a catalytic RNA within RNase P and its legacy. [PDF]
Kirsebom LA, Liu F, McClain WH.
europepmc +1 more source
Protein cofactors and substrate influence Mg2+-dependent structural changes in the catalytic RNA of archaeal RNase P. [PDF]
Marathe IA+5 more
europepmc +1 more source
Human Schlafen 14 Cleavage of Short Double‐Stranded RNAs Underpins its Antiviral Activity
SLFN14 is associated with human diseases. SLFN14 is found to cleave RNAs containing short duplexes. The cryo‐EM structures of SLFN14 and SLFN14‐hairpin RNA complex reveal that SLFN14 assembles into a ring‐like dimer; two RNase domains form an RNA‐binding groove accommodating a hairpin RNA.
Mengyun Li+8 more
wiley +1 more source