Discovery, structure, mechanisms, and evolution of protein-only RNase P enzymes. [PDF]
Rossmanith W, Giegé P, Hartmann RK.
europepmc +1 more source
Bi-allelic variants in the mitochondrial RNase P subunit PRORP cause mitochondrial tRNA processing defects and pleiotropic multisystem presentations. [PDF]
Hochberg I+40 more
europepmc +1 more source
Engineered Cas12j‐8 is a Versatile Platform for Multiplexed Genome Modulation in Mammalian Cells
Engineered through structure‐guided protein engineering, enCas12j‐8 significantly enhances the editing efficiency of compact Cas12j‐8 while maintaining high specificity. It enables efficient multiplexed genome editing and base editing using a single crRNA array, demonstrating broad applicability and therapeutic potential in genome engineering ...
Ru Meng+14 more
wiley +1 more source
Partial reconstitution of human RNase P in HeLa cells between its RNA subunit with an affinity tag and the intact protein components [PDF]
Yong Li
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Coevolution of RNA and protein subunits in RNase P and RNase MRP, two RNA processing enzymes. [PDF]
Zhou B+5 more
europepmc +1 more source
Regulation of bacterial RNase P ribozyme reaction by divalent cation and guide DNA [PDF]
Tomoaki Ando+3 more
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Validation of a duplex PCR technique using the gen E and RNase P for the diagnosis of SARS-CoV-2. [PDF]
Palacio Rua K+5 more
europepmc +1 more source
Comparative study on tertiary contacts and folding of RNase P RNAs from a psychrophilic, a mesophilic/radiation-resistant, and a thermophilic bacterium. [PDF]
Marszalkowski M+6 more
europepmc +1 more source