Results 241 to 250 of about 18,946,844 (347)

Differential association of protein subunits with the human RNase MRP and RNase P complexes [PDF]

, 2006
Tim J. M. Welting, Bastiaan J. Kikkert, Walther J. van Venrooij, Ger J.M. Pruijn   +3 more
openalex   +1 more source

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

Advanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li, Hang Zheng, Yuxing Lin, Ziwei Zhao, Yijia Mai, Zhangrong Lou, Qiang Liu, Zhao Ma, Chengjun Wu   +8 more
wiley   +1 more source

Structural basis of transfer RNA processing by bacterial minimal RNase P. [PDF]

Nat Commun
Teramoto T, Koyasu T, Yokogawa T, Adachi N, Mayanagi K, Nakamura T, Senda T, Kakuta Y.   +7 more
europepmc   +1 more source

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

Primer and Probe sequences for DENV serotypes, CHIKV, and Internal control (RNase P).

Mansi Rajendra Malik (22032949), Samruddhi Walaskar (22032952), Ritika Majji (22032955), Deepanraj SP (22032958), Shruthi Uppoor (22032961), Thrilok Chandra KV (22032964), Madhusudhan H.N (22032967), Balasundar A.S (22032970), Rakesh Kumar Mishra (6691833), Farah Ishtiaq (3816469)   +9 more
openalex   +1 more source

Antisense Inhibition of RNase P [PDF]

Journal of Biological Chemistry, 2006
Heike Gruegelsiepe, Ole Brandt, Roland K. Hartmann   +2 more
openaire   +1 more source

RNase P generated tRF^Ser-GCT promotes fat storage in adipocytes via Adrb2 signaling. [PDF]

J Biol Chem
Shen L, Lei Y, Zhao X, Wang X, Chen D, Wang K, Zhong Y, Liao T, Yang Y, Chen L, Zhao Y, Niu L, Zhou X, Gan M, Zhu L.   +14 more
europepmc   +1 more source

RNA binding properties of conserved protein subunits of human RNase P

, 2011
Robert C. Reiner, Noa Alfiya-Mor, Mishka Berrebi-Demma, Donna Wesolowski, Sidney Altman, Nayef Jarrous   +5 more
openalex   +1 more source

Interplay between substrate recognition, 5′ end tRNA processing and methylation activity of human mitochondrial RNase P [PDF]

, 2019
Agnes Karasik, Carol A. Fierke, Markos Koutmos   +2 more
openalex   +1 more source

p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway

Advanced Science, EarlyView.
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa, Teh‐Wei Wang, Satoshi Kawakami, Shota Tanimoto, Kiyoshi Yamaguchi, Taketomo Kido, Masamichi Kimura, Tsunekazu Hishima, Yuki T. Okamura, Satotaka Omori, Takumi Iritani, Toshikaze Chiba, Takehiro Jimbo, Michio Katano, Kansuporn Kamataki, Ryoichi Yokoyama, Eigo Shimizu, Kiminori Kimura, Satoshi Yamzaki, Seiya Imoto, Yoichi Furukawa, Atsushi Miyajima, Yoshikazu Johmura, Makoto Nakanishi   +23 more
wiley   +1 more source