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Yeast mitochondrial RNase P: an unusual member of the RNase P enzyme family
1995We review here our studies of the tRNA processing enzyme, RNase P. Yeast mitochondrial RNase P contains an AU-rich mitochondrial coded RNA which varies in size in different yeasts. All of these RNAs contain two short sequences with similarity to two sequences found in all RNase P RNAs.
G.-J. Gao +3 more
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Characterization of RNase P RNA Activity
2012The principle task of the ubiquitous enzyme RNase P is the generation of mature tRNA 5'-ends by removing precursor sequences from tRNA primary transcripts (Trends Genet 19:561-569, 2003; Crit Rev Biochem Mol Biol 41:77-102, 2006; Trends Biochem Sci 31:333-341, 2006).
Markus, Gössringer +2 more
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Roles of RNase P and Its Subunits
Trends in Genetics, 2017Recent studies show that nuclear RNase P is linked to chromatin structure and function. Thus, variants of this ribonucleoprotein (RNP) complex bind to chromatin of small noncoding RNA genes; integrate into initiation complexes of RNA polymerase (Pol) III; repress histone H3.3 nucleosome deposition; control tRNA and PIWI-interacting RNA (piRNA) gene ...
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Further characterization of human RNase MRP/RNase P and related autoantibodies
Molecular Biology Reports, 1998We characterized a panel of human RNase MRP/RNase P autoantibodies by immunoprecipitation, immunodepletion, immunoaffinity purification and immunoblotting. We report on the protein spectrum that is recognized by RNase MRP/RNase P autoantibodies. We also describe another, related patient serum that based on these assays does not immunoprecipitate RNase ...
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Nature structural biology, 2000
In 1989, Sidney Altman and Thomas R. Cech shared the Nobel Prize in Chemistry for their discovery of catalytic properties of RNA. Cech was studying the splicing of RNA in a unicellular organism called Tetrahymena thermophila. He found that the precursor RNA could splice in vitro in the absence of proteins.
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In 1989, Sidney Altman and Thomas R. Cech shared the Nobel Prize in Chemistry for their discovery of catalytic properties of RNA. Cech was studying the splicing of RNA in a unicellular organism called Tetrahymena thermophila. He found that the precursor RNA could splice in vitro in the absence of proteins.
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RNase E: At the Interface of Bacterial RNA Processing and Decay
Nature Reviews Microbiology, 2013George A. Mackie
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Bacterial RNase P: A New View of an Ancient Enzyme
Nature Reviews Microbiology, 2006Norman R. Pace, Alexei V Kazantsev
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When All's Zed and Done: The Structure and Function of RNase Z in Prokaryotes
Nature Reviews Microbiology, 2007Ciaran Condon +1 more
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