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Safety evaluation of the food enzyme ribonuclease P from the non‐genetically modified Penicillium citrinum strain AE‐RP‐4 [PDF]

open access: yesEFSA Journal, 2023
The food enzyme ribonuclease P (EC 3.1.26.5) is produced with the non‐genetically modified Penicillium citrinum strain AE‐RP‐4 by Amano Enzyme Inc. It is intended to be used in yeast processing only for the production of yeast extract.
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP)   +26 more
doaj   +2 more sources

New insights into the role of ribonuclease P protein subunit p30 from tumor to internal reference [PDF]

open access: yesFrontiers in Oncology, 2022
Ribonuclease P protein subunit p30 (RPP30) is a highly conserved housekeeping gene that exists in many species and tissues throughout the three life kingdoms (archaea, bacteria, and eukaryotes).
Junchao Wu   +7 more
doaj   +2 more sources

Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P [PDF]

open access: yesNature Communications, 2022
Binding of precursor tRNAs (ptRNAs) by bacterial ribonuclease P (RNase P) involves an encounter complex (ES) that isomerizes to a catalytic conformation (ES*).
Jiaqiang Zhu   +5 more
doaj   +2 more sources

Production of ovine Pancreatic Ribonuclease and investigation of enzyme characteristics [PDF]

open access: yesپژوهشهای علوم دامی ایران, 2021
Introduction Obviously, the recent decades strategy in cancer therapy, anticancer drug discovery and drug improvement is to characterize, distinguish and validate the most promising cancer-related molecular targets to which new drugs can be designed. The
mahsa Zabetian   +3 more
doaj   +1 more source

Proteins Rpr2 and Pop3 increase the activity and thermal stability of yeast RNase P

open access: yesRNA Biology, 2023
RNA-based enzyme RNase P is a ribonucleoprotein complex responsible primarily for 5’-maturation of tRNAs. S. cerevisiae RNase P comprises a catalytic RNA component and nine proteins. The assembly and maturation of S.
Anna Perederina   +2 more
doaj   +1 more source

RPP40 is a prognostic biomarker and correlated with tumor microenvironment in uterine corpus endometrial carcinoma

open access: yesFrontiers in Oncology, 2022
Ribonuclease P/MRP Subunit P40 (RPP40), a component of ribonuclease P and multimeric ribonuclease P complex, was reported as one of the promoting factors for the chemoresistance of acute myeloid leukemia and a recurrence predictor of early-stage triple ...
Jianming Tang   +4 more
doaj   +1 more source

The Ribonuclease P database [PDF]

open access: yesNucleic Acids Research, 1994
The Ribonuclease P Sequence database is a compilation of RNase P sequences, sequence alignments, secondary structures, three-dimensional models, and accessory information. In its initial form, the database contains information on RNase P RNA in bacteria and archaea, and RNase P protein in bacteria.
J W, Brown   +3 more
openaire   +2 more sources

Catalytic RNA Oligomers Formed by Co-Oligomerization of a Pair of Bimolecular RNase P Ribozymes

open access: yesMolecules, 2022
Naturally occurring ribozymes with a modular architecture are promising platforms for construction of RNA nanostructures because modular redesign enables their oligomerization.
Mst. Ayesha Siddika   +7 more
doaj   +1 more source

P finder: genomic and metagenomic annotation of RNase P RNA gene (rnpB)

open access: yesBMC Genomics, 2020
Background The rnpB gene encodes for an essential catalytic RNA (RNase P). Like other essential RNAs, RNase P’s sequence is highly variable. However, unlike other essential RNAs (i.e.
J. Christopher Ellis
doaj   +1 more source

Dissecting Monomer-Dimer Equilibrium of an RNase P Protein Provides Insight Into the Synergistic Flexibility of 5’ Leader Pre-tRNA Recognition

open access: yesFrontiers in Molecular Biosciences, 2021
Ribonuclease P (RNase P) is a universal RNA-protein endonuclease that catalyzes 5’ precursor-tRNA (ptRNA) processing. The RNase P RNA plays the catalytic role in ptRNA processing; however, the RNase P protein is required for catalysis in vivo and ...
Danyun Zeng   +4 more
doaj   +1 more source

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