Results 251 to 260 of about 18,946,844 (347)

hPop5, a Protein Subunit of the Human RNase MRP and RNase P Endoribonucleases [PDF]

, 2001
Hans van Eenennaam, Dorien Lugtenberg, Judith Vogelzangs, Walther J. van Venrooij, Ger J.M. Pruijn   +4 more
openalex   +1 more source

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

PUM1 and RNase P genes as potential cell-free DNA markers in breast cancer. [PDF]

J Clin Lab Anal, 2021
Murillo Carrasco A, Acosta O, Ponce J, Cotrina J, Aguilar A, Araujo J, Rebaza P, Pinto JA, Fujita R, Buleje J.   +9 more
europepmc   +1 more source

The regulatory effect of CsrA on cstA, glgCAP and flhDC in an RNase P ts mutant Escherichia coli

, 2017
Zeinalabedin Hilow
openalex   +1 more source

Design and isolation of ribozyme-substrate pairs using RNase P-based ribozymes containing altered substrate binding sites [PDF]

, 1999
Evelyn M. Mobley, Tao Pan
openalex   +1 more source

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

Advanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source

Reduction of <i>Drosophila</i> Mitochondrial RNase P in Skeletal and Heart Muscle Causes Muscle Degeneration, Cardiomyopathy, and Heart Arrhythmia. [PDF]

Front Cell Dev Biol, 2022
Saoji M, Petersen CE, Sen A, Tripoli BA, Smyth JT, Cox RT.   +5 more
europepmc   +1 more source

Characterization of conserved sequence elements in eukaryotic RNase P RNA reveals roles in holoenzyme assembly and tRNA processing [PDF]

, 2005
Shaohua Xiao, Jeremy J. Day-Storms, Chatchawan Srisawat, Carol A. Fierke, David R. Engelke   +4 more
openalex   +1 more source

Catalysis by RNase P RNA [PDF]

Journal of Biological Chemistry, 2003
Tina Persson, Simona Cuzic, Roland K. Hartmann   +2 more
openaire   +1 more source

Intercellular Horizontal Transfer of TXNDC5 mRNA via Extracellular Vesicles Contributes to Tumor‐Associated Macrophage‐Mediated Prostate Cancer Metastasis

Advanced Science, EarlyView.
This study investigates the role of M2 macrophage‐derived extracellular vesicles (M2 EVs) in prostate cancer (PCa) metastasis. Mechanistically, M2 EVs horizontally transfer TXNDC5 mRNA to PCa cells, where the molecule induces the mesenchymal‐like state (MLS), enhancing PCa migration and invasion.
Cong Hu, Tianyang Wu, Jiayi Wang, Xinxing Du, Xinrui Wu, Yanhao Dong, Zehong Peng, Penghui Liao, Zirui Guo, Zheyu Liu, Kenneth J Pienta, Yinjie Zhu, Jiahua Pan, Liang Dong, Wei Xue   +14 more
wiley   +1 more source