Results 71 to 80 of about 5,005,660 (350)

Post-Disaster Road Reconstruction in Aceh - Local Governments’ Role in Road Maintenance [PDF]

open access: yes, 2012
Many studies have shown the importance of improved road infrastructure towards economic development of a region through economic agglomeration and widened business network coverage resulting from better access and higher mobility. However, such benefit
Amaratunga, Dilanthi, Hayat, Ezri
core  

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

A functional road classification with data mining techniques

open access: yesTransport, 2014
The current international road standards, in order to give organization and safety, promote the classification of roads according to their technical and functional characteristics beyond their administrative membership, but the procedures are yet ...
Antonino D’Andrea   +3 more
doaj   +1 more source

Road User Interactions: Patterns of Road Use and Perception of Driving Risk [PDF]

open access: yes, 2002
The goal of the Road User Interactions research programme is a better understanding of the human factors of our road transport system: road user demographics, risk perceptions of road users, and the driving attitudes of various road user groups.
Baas, Peter H., Charlton, Samuel G.
core  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Economically Optimal Road Subnetwork

open access: yesCommunications, 2014
The paper deals with the following situation: An area is served by a transportation network, usually the road one. The current quality of the network is not satisfactory for the owner (e.g.
Anna Cerna, Jan Cerny, Vladimir Pribyl
doaj   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Development of Intelligent Transport Systems in Russia: problems and solutions. New stage

open access: yesИнтеллект. Инновации. Инвестиции, 2020
The situation with the development of intelligent transport systems (ITS) in Russia is characterized. The main problems of the development of ITS in our country are considered.
A. I. Solodkiy
doaj   +1 more source

Road: artists and the stop the M11 link road campaign 1984 - 1994 [PDF]

open access: yes, 2012
The project 'Road' is an archive of text, images and oral recordings that document the living history of the 'No M11 Link Road' campaign in East London (Leyton, Leytonstone and Wanstead) from 1984 to 1995, and the people that lived in and visited the ...
Liley, Hannah   +2 more
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

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