Results 61 to 70 of about 1,197,719 (300)
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Towards a Distributed Quantum Computing Ecosystem
The Quantum Internet, by enabling quantum communications among remote quantum nodes, is a network capable of supporting functionalities with no direct counterpart in the classical world.
Cacciapuoti, Angela Sara +2 more
core +1 more source
Non-invasive characterisation of road subgrade with towed-array capacitive resistivity imaging [PDF]
A towed-array Capacitive Resistivity Imaging (CRI) system has been used in a controlled experiment to acquire multi-channel high-resolution ERT data on an asphalt road. Results from a CRI survey on a purpose-built trial road are discussed and compared to
Beamish, D. +3 more
core +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Pavement damage decay performance of ordinary national and provincial trunk lines
To overcome the limitations inherent in traditional road network-level models for predicting pavement damage decay on ordinary national and provincial trunk lines, this investigation draws on comprehensive detection and evaluation data from A province in
Jianguo Rong +3 more
doaj +1 more source
Demonstrations for Children of All Age- The Cork Canon [PDF]
Demonstrations are one of the most useful techniques for teaching science to anyone, regardless of age. Demonstrations attract attention and normally make the observer want to learn more about what is happening. This paper reports on The Cork Cannon, one
Thornton, S.
core +1 more source
Intercompartmental communication in senescence
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source
Analysis of Fume Enrichment Methods and Release Patterns of Plant-Mixed Asphalt Mixtures
The disorderly emission and poor treatment effect of asphalt mixture fume in asphalt mixing stations have caused huge harm to the natural environment and human health.
Tengfei Nian +4 more
doaj +1 more source
A Cyberinfrastructure for BigData Transportation Engineering [PDF]
Big Data-driven transportation engineering has the potential to improve utilization of road infrastructure, decrease traffic fatalities, improve fuel consumption, decrease construction worker injuries, among others.
Islam, Md Johirul +4 more
core +3 more sources
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source

