Results 51 to 60 of about 8,402,433 (327)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Self-organized Natural Roads for Predicting Traffic Flow: A Sensitivity Study

open access: yes, 2008
In this paper, we extended road-based topological analysis to both nationwide and urban road networks, and concentrated on a sensitivity study with respect to the formation of self-organized natural roads based on the Gestalt principle of good continuity.
Jiang, Bin, Yin, Junjun, Zhao, Sijian
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Crossing Patterns in Nonplanar Road Networks

open access: yes, 2017
We define the crossing graph of a given embedded graph (such as a road network) to be a graph with a vertex for each edge of the embedding, with two crossing graph vertices adjacent when the corresponding two edges of the embedding cross each other.
Chung Fan R. K.   +2 more
core   +1 more source

An application of Dijkstra’s algorithm model in finding shortest travel time in KLCC [PDF]

open access: yes, 2020
Nowadays, traffic congestion or also known as traffic jammed is one of the common routing problems that usually occur on road networks. Routing problems becomes one of the big concern that most of the develop country must face including ...
Abdul Rahim, Nur Hanis   +6 more
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The SSP-Tree: A Method for Distributed Processing of Range Monitoring Queries in Road Networks

open access: yesISPRS International Journal of Geo-Information, 2017
This paper addresses the problem of processing range monitoring queries, each of which continuously retrieves moving objects that are currently located within a given query range.
HaRim Jung, Ung-Mo Kim
doaj   +1 more source

An evaluation of different provision strategies for scaled-up container-based sanitation

open access: yesH2Open Journal, 2021
Container-based sanitation (CBS) is increasingly used to provide safely managed sanitation in low-income urban settlements. However, questions remain around the viability of scaling up the technology, partly because it relies on regular emptying and ...
Charlie Ferguson   +7 more
doaj   +1 more source

Flood risk assessment for road infrastructures using Bayesian networks: case study of Santarem - Portugal

open access: yesActa Polytechnica CTU Proceedings, 2022
Assessing flood risks on road infrastructures is critical for the definition of mitigation strategies and adaptation processes. Some efforts have been made to conduct a regional flood risk assessment to support the decision-making process of exposed ...
Erica Arango   +4 more
doaj   +1 more source

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