Results 71 to 80 of about 8,402,433 (327)
The Traffic Phases of Road Networks [PDF]
, 2013 We study the relation between the average traffic flow and the vehicle density on road networks that we call 2D-traffic fundamental diagram. We show that this diagram presents mainly four phases. We analyze different cases.
Avenue De L’europe +3 more
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Online Multi-Skilled Task Assignment on Road Networks
IEEE Access, 2019 With the development of smart phones and online to offline, spatial platforms, such as TaskRabbit, are getting famous and popular. Tasks on these platforms have three main characters: they are in real-time dynamic scenario, they are on the road networks,
Yu Liang +3 more
doaj +1 more source
Finding Multiple New Optimal Locations in a Road Network
, 2016 We study the problem of optimal location querying for location based services in road networks, which aims to find locations for new servers or facilities. The existing optimal solutions on this problem consider only the cases with one new server.
Cabello S. +5 more
core +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Journal of Physics: ComplexityWalking and cycling, commonly referred to as active travel, have become integral components of modern transport planning. Recently, there has been growing recognition of the substantial role that active travel can play in making cities more liveable ...
Ivann Schlosser +4 more
doaj +1 more source
Networks and Cities: An Information Perspective
, 2005 Traffic is constrained by the information involved in locating the receiver and the physical distance between sender and receiver. We here focus on the former, and investigate traffic in the perspective of information handling. We re-plot the road map of
Minnhagen, P. +3 more
core +1 more source
Intercompartmental communication in senescence
FEBS Open Bio, EarlyView.Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source