Results 61 to 70 of about 8,402,433 (327)

Fast simulation for Road Traffic Network [PDF]

open access: yesRAIRO - Operations Research, 2001
Summary: In this paper we present a method to perform fast simulation of large Markovian systems. This method is based on the use of three concepts: Markov chain uniformization, event-driven dynamics, and modularity. An application of urban traffic simulation is presented to illustrate the performance of our approach.
Ycart, Bernard   +3 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Phase Noise Suppression Algorithm Based on Modified LLR Metric in SC-FDMA System

open access: yesJournal of Electrical and Computer Engineering, 2017
In single-carrier frequency-division multiple-access (SC-FDMA) receivers in the long-term evolution uplink, phase noise is one of the major radio-frequency front-end impairments that degrade system performance. To address this issue, we propose a new log-
Zijie Xu, Guangliang Ren
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Flood and landslide exposure awareness for mitigation of road network performance: a community-based approach

open access: yesJurnal Ilmiah SINERGI
Natural disasters in the form of floods and erosion in remote area road networks pose challenges for the government. The involvement of community-based disaster management can make it easier for stakeholders to carry out disaster mitigation intelligently.
Andri Irfan Rifai   +4 more
doaj   +1 more source

Extracting Main Center Pattern from Road Networks Using Density-Based Clustering with Fuzzy Neighborhood

open access: yesISPRS International Journal of Geo-Information, 2019
The spatial pattern is a kind of typical structural knowledge that reflects the distribution characteristics of object groups. As an important semantic pattern of road networks, the city center is significant to urban analysis, cartographic ...
Xiaojie Cui   +6 more
doaj   +1 more source

Mean-Field-Type Games in Engineering

open access: yes, 2017
A mean-field-type game is a game in which the instantaneous payoffs and/or the state dynamics functions involve not only the state and the action profile but also the joint distributions of state-action pairs.
Djehiche, Boualem   +2 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Learning Embeddings of Intersections on Road Networks

open access: yesSIGSPATIAL/GIS, 2019
Road network is a basic component of intelligent transportation systems (ITS) in smart city. Informative representation of road networks is important as it is essential to a wide variety of ITS applications.
Meng-xiang Wang   +3 more
semanticscholar   +1 more source

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