Results 81 to 90 of about 1,793,599 (278)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Preparation and Properties of Waterborne Polyurethane and SBS Composite-Modified Emulsified Asphalt

open access: yesApplied Sciences
To address the issue of insufficient durability of traditional modified emulsified asphalt in the application of cold mix and cold paving anti-skid wear layers, this study utilizes cationic waterborne polyurethane (PU+) for composite modification to ...
Ruiqi Chen, Wen Xu, Yixing Chen
doaj   +1 more source

Performance Evaluation of Road Traffic Control Using a Fuzzy Cellular Model

open access: yes, 2011
In this paper a method is proposed for performance evaluation of road traffic control systems. The method is designed to be implemented in an on-line simulation environment, which enables optimisation of adaptive traffic control strategies.
A.A. Kurzhanskiy   +12 more
core   +1 more source

The road to lightweight performance

open access: yesReinforced Plastics, 2008
With over 400 attendees and 60 plus papers, eight keynotes, and one panel discussion, the 2008 Society of Plastics Engineers (SPE) Automotive Composite Conference and Exposition (ACCE)'s ‘The Road to Lightweight Performance’ convened in Troy, Michigan, in the USA for three full days of presentations, panel discussions and networking receptions.
null Mike, Pam Brady
openaire   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Research on the Properties of Nano-Al2O3- and Nano-SiO2-Modified Bio-Asphalt and Mixtures

open access: yesBuildings
Bio-oil as a substitute or modifier for petroleum asphalt has significant environmental, economic, and sustainable development implications. However, the insufficient high-temperature and anti-aging characteristics of bio-asphalt lead to the limited ...
Wei Qiao   +3 more
doaj   +1 more source

Crash risk estimation and assessment tool [PDF]

open access: yes, 2010
Currently in Australia, there are no decision support tools for traffic and transport engineers to assess the crash risk potential of proposed road projects at design level.
Jurewicz, Chris, Thompson, Bruce
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Study of Low-Content Epoxy Asphalt Mixture Applied to the Road

open access: yesBuildings
To realize the application of epoxy asphalt concrete on roads and solve the problem of the high cost of epoxy asphalt concrete and the causes of bulging in the construction process, a low-content epoxy asphalt mixture was experimentally studied ...
Xiaodong Li   +6 more
doaj   +1 more source

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