Results 61 to 70 of about 24,468 (303)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Marginality and the Third Space of Unadopted Plotlander Roads [PDF]

open access: yesSpace and Culture, 2017
This article explores the characteristics and relationships of marginality in informal space and plotlander housing in the context of Homi K. Bhabha’s cultural hybridity and Third Space. To illustrate and examine the processes of marginalization that defined informal space in the United Kingdom, this article will critically analyze
openaire   +1 more source

Traffic Microsimulation Study to Evaluate the Effect of Type and Spacing of Traffic Calming Devices on Capacity

open access: yes, 2011
Traffic calming is widely implemented to improve road safety. However, the implementation of traffic calming devices implies less capacity of cross-town roads.
Ana Tsui Moreno   +7 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Development and analysis of road lighting : road surfaces and mesopic dimensioning [PDF]

open access: yes, 2011
This work starts with a short introduction in which the energy consumption, proportion of different types of light sources, and procedures that have been introduced concerning energy saving in outdoor lighting are overviewed.
Ylinen, Anne-Mari
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Determining Appropriate Lane-Changing Spacing for Off-Ramp Areas of Urban Expressways [PDF]

open access: yes, 2019
Congestion has become a significant issue in recent years and has greatly affected the efficiency of urban traffic operation. Random and disorderly lane-changing behavior greatly reduces traffic capacity and safety.
Zihan Zhang   +4 more
core   +2 more sources

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Optimal Configuration Research of Plant Landscapes under Combined Horizontal and Vertical Curves on Mountainous Roads

open access: yesApplied Sciences
The combination of horizontal curves and gradients can lead to visual perception errors by drivers, resulting in risky operations. While plant landscapes serve to guide road alignment and alleviate driver stress, irrational plant landscapes can obstruct ...
Hao Li   +3 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

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