Results 61 to 70 of about 927,597 (297)

Simple Obstacle Avoidance Algorithm for Rehabilitation Robots [PDF]

open access: yes, 2007
The efficiency of a rehabilitation robot is improved by offering record-and-replay to operate the robot. While automatically moving to a stored target (replay) collisions of the robot with obstacles in its work space must be avoided.
Römer, G.R.B.   +2 more
core   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Visual task identification and characterisation using polynomial models [PDF]

open access: yes, 2006
Developing robust and reliable control code for autonomous mobile robots is difficult, because the interaction between a physical robot and the environment is highly complex, subject to noise and variation, and therefore partly unpredictable.
Akanyeti, O.   +4 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Robotic Endoscopy [PDF]

open access: yesVisceral Medicine, 2018
Endoscopes extend the eyes of the physician into the patient's body. They are widely used in gastrointestinal (GI) diagnostics and minimally invasive surgery. Endoscopes can be classified into 3 types: rigid, flexible, and capsule endoscopes. Rigid and flexible endoscopes are traditionally held and manipulated by the physician to visualize the region ...
Zheng, Li, Philip Wai-Yan, Chiu
openaire   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

A diffusion model-based image generation framework for underwater object detection

open access: yesCommunications Engineering
Underwater object detection plays a crucial role in applications such as marine ecological monitoring and underwater rescue operations. However, challenges such as limited underwater data availability and low scene diversity hinder detection accuracy. In
Yaoming Zhuang   +8 more
doaj   +1 more source

Contact Model of Revolute Joint with Clearance Based on Fractal Theory

open access: yesChinese Journal of Mechanical Engineering, 2018
The contact stiffness of a mechanical bonding surface is an important parameter in determining the normal and radial contact force. To improve the calculation accuracy of the contact force model, the surface roughness of the bonding surface and the ...
Shi-Hua Li   +4 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Collision Avoidance of Multi-UUV Systems Based on Deep Reinforcement Learning in Complex Marine Environments

open access: yesJournal of Marine Science and Engineering
For multiple unmanned underwater vehicles (UUVs) systems, obstacle avoidance during cooperative operation in complex marine environments remains a challenging issue.
Fuyu Cao   +5 more
doaj   +1 more source

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