Results 41 to 50 of about 134,994 (267)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Control Strategies of Gecko’s Toe in Response to Reduced Gravity

open access: yesApplied Sciences, 2020
Shear-induced adhesion is one of the key properties for the gecko moving safely and quickly in a three-dimensional environment. The control strategies of such locomotion strongly relying on adhesion are still not well understood.
Zhongyuan Wang   +2 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

A diffusion model-based image generation framework for underwater object detection

open access: yesCommunications Engineering
Underwater object detection plays a crucial role in applications such as marine ecological monitoring and underwater rescue operations. However, challenges such as limited underwater data availability and low scene diversity hinder detection accuracy. In
Yaoming Zhuang   +8 more
doaj   +1 more source

Social Robotics and Societies of Robots

open access: yesThe Information Society, 2015
The sustainability of social robotics, like other ambitious research programs, depends on the identification of lines of inquiry that are coherent with its visionary goals while satisfying more stringent constraints of feasibility and near-term payoffs.
Antonio Bicchi, TAMBURRINI, GUGLIELMO
openaire   +3 more sources

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Theta Frequency Band in the EEG Signal as Neurocognitive Indicator of Cognitive Load for Collaborative Tasks Involving Robot Teleoperation

open access: yesHuman Behavior and Emerging Technologies
The aim of the present study was to identify metrics of cognitive effort during robot teleoperation in a social context of joint collaborative task performed with another human user.
Magda Mustile   +7 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Robotic Simulations, Simulations of Robots

open access: yesMinds and Machines, 2019
Simulation studies have been carried out in robotics for a variety of epistemic and practical purposes. Here it is argued that two broad classes of simulation studies can be identified in robotics research. The first one is exemplified by the use of robotic systems to acquire knowledge on living systems in so-called biorobotics, while the second class ...
Edoardo Datteri, Viola Schiaffonati
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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