Results 61 to 70 of about 1,487,845 (265)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A novel robust generalized backstepping controlling method for a class of nonlinear systems

Cogent Engineering, 2017
This study is aimed at introducing a new robust control strategy in developed backstepping method designed for a special class of nonlinear systems, which does not require any information on the upper bound of parametric uncertainties.
Malek Ghanavati, Karim Salahshoor, Mohammad Reza Jahed Motlagh, Amin Ramezani, Ali Moarefianpour   +4 more
doaj   +1 more source

Robust Longitudinal Aircraft- Control Based on an Adaptive Fuzzy-Logic Algorithm

Sultan Qaboos University Journal for Science, 2002
To study the aircraft response to a fast pull-up manoeuvre, a short period approximation of the longitudinal model is considered. The model is highly nonlinear and includes parametric uncertainties.
Abdel- Latif Elshafei
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Robust virtual‐vector model predictive control of permanent‐magnet motor considering D‐Q axis inductance parameter uncertainty

IET Electric Power Applications
To suppress parameter mismatch and improve the output performance of model predictive control (MPC), a new robust virtual‐vector MPC strategy is proposed for a five‐phase permanent‐magnet motor in this study.
Xingke An, Zhengmeng Liu, Qian Chen, Guohai Liu   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Universally Robust Quantum Control

Physical Review Letters
We study the robustness of the evolution of a quantum system against small uncontrolled variations in parameters in the Hamiltonian. We show that the fidelity susceptibility, which quantifies the perturbative error to leading order, can be expressed in superoperator form and use this to derive control pulses which are robust to any class of systematic ...
Pablo M. Poggi, Gabriele De Chiara, Steve Campbell, Anthony Kiely   +3 more
openaire   +6 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Robust regret optimal control

International Journal of Robust and Nonlinear Control
SummaryThis paper presents a synthesis method for robust, regret optimal control. The plant is modeled in discrete‐time by an uncertain linear time‐invariant (LTI) system. An optimal non‐causal controller is constructed using the nominal plant model and given full knowledge of the disturbance.
Jietian Liu, Peter Seiler 0001
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source