Results 61 to 70 of about 3,738,279 (288)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Combined simple cautious and robust control for parameter and disturbance bounded distributions [PDF]
, 1994 The qualities and drawbacks of two control methods to cope with process uncertainty are considered: cautious control which only uses statistics, and robust control which only uses the bounds of the process uncertainty.
Löhnberg, P., Römer, G.R.B.E.
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Fractional robust control of ligthly damped systems [PDF]
, 2006 The article proposes a method to design a robust controller ensuring the damping ratio of a closed-loop control. The method uses a contour para-meterized by the damping ratio in the Nichols plane and the complex non-integer (or fractional)differentiation
Janat, Yaman +3 more
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Design of an optimal non-integer order controller for controlling a servo system [PDF]
Journal on Processing and Energy in Agriculture, 2016 This paper presents several methods for optimal parameter tuning of non-integer order controllers for controlling a servo system. The servo system used for the purpose of the analysis was a laboratory servo system with both linear and non-linear ...
Jakovljević Boris +3 more
doaj
Mixed sensitivity control: a non-iterative approach
Systems Science & Control Engineering, 2020 Recent analytical solutions to Mixed Sensitivity Control (MSC) are developed and compared with standard MSC based on γ-iteration. The proposed MSC solution gives conditions for strong stability and overcomes the pole-zero cancellations between the plant ...
R. Galindo Orozco
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Sampling-based Learning Control for Quantum Systems with Uncertainties
, 2015 Robust control design for quantum systems has been recognized as a key task in the development of practical quantum technology. In this paper, we present a systematic numerical methodology of sampling-based learning control (SLC) for control design of ...
Chen, Chunlin +5 more
core +1 more source