Results 81 to 90 of about 3,216,313 (259)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Networked PID control design : a pseudo-probabilistic robust approach [PDF]

open access: yes, 2009
Networked Control Systems (NCS) are feedback/feed-forward control systems where control components (sensors, actuators and controllers) are distributed across a common communication network.
Katebi, M.R., Recalde Camacho, L.
core  

Robust Fault Diagnosis by Optimal Input Design for Self-sensing Systems

open access: yes, 2017
This paper presents a methodology for model based robust fault diagnosis and a methodology for input design to obtain optimal diagnosis of faults. The proposed algorithm is suitable for real time implementation. Issues of robustness are addressed for the
Khalate, Amol   +2 more
core   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Latest advances and developments in aluminum shape casting [PDF]

open access: yesChina Foundry, 2013
With the increasing use of aluminum shape castings in structural applications in the automotive and aerospace industries, assurance of cast product integrity and performance has become critical in both design and manufacturing.
Qigui Wang
doaj  

Robust Mechanism Design [PDF]

open access: yes
The mechanism design literature assumes too much common knowledge of the environment among the players and planner. We relax this assumption by studying implementation on richer type spaces. We ask when ex post implementation is equivalent to interim (or
Dirk Bergemann, Stephen Morris
core  

Design and implementation of robust embedded processor for cryptographic applications [PDF]

open access: yes, 2010
Practical implementations of cryptographic algorithms are vulnerable to side-channel analysis and fault attacks. Thus, some masking and fault detection algorithms must be incorporated into these implementations.
Erdem, Serdar Suer   +5 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Robust Optimization Design of Subway Underframe Based on Dual Response Surface

open access: yes机车电传动, 2019
In order to reduce the dispersion of the objective response due to uncertain factors in the subway underframe’s optimization process, a robust optimization design method based on dual response surface model was proposed.
Yonghua LI   +5 more
doaj  

Efficient Robust Optimization of Metal Forming Processes using a Sequential Metamodel Based Strategy [PDF]

open access: yes, 2011
The coupling of Finite Element (FE) simulations to mathematical optimization techniques has contributed significantly to product improvements and cost reductions in the metal forming industries.
Boogaard, A.H. van den   +2 more
core   +1 more source

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