Results 91 to 100 of about 376,109 (314)

Robust high-cycle fatigue stress threshold optimization under uncertain loadings

Latin American Journal of Solids and Structures
This paper proposes a strategy to achieve robust optimization of structures against high-cycle fatigue when a potentially large number of uncertain load cases are considered.
Alfredo R. de Faria, Roberto T. C. Frota Jr.   +1 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

A novel robust multi-objective evolutionary optimization algorithm based on surviving rate

Complex & Intelligent Systems
Multi-objective evolutionary optimization is widely utilized in industrial design. Despite the success of multi-objective evolutionary optimization algorithms in addressing complex optimization problems, research focusing on input disturbances remains ...
Wenxiang Jiang, Kai Gao, Shuwei Zhu, Lihong Xu   +3 more
doaj   +1 more source

Nonlinear distributionally robust optimization

Mathematical Programming
This article focuses on a class of distributionally robust optimization (DRO) problems where, unlike the growing body of the literature, the objective function is potentially nonlinear in the distribution. Existing methods to optimize nonlinear functions in probability space use the Frechet derivatives, which present theoretical and computational ...
Mohammed Rayyan Sheriff, Peyman Mohajerin Esfahani   +1 more
openaire   +3 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Distributionally Robust Optimization with Polynomial Robust Constraints

Journal of Global Optimization
25 ...
Jiawang Nie, Suhan Zhong
openaire   +3 more sources

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Robust production optimization of gas-lifted oil fields [PDF]

, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Automação e Sistemas, Florianópolis, 2015.Com a crescente demanda por energia fóssil as operadoras petrolíferas têm buscado ...
Hülse, Eduardo Otte
core  

A Multiobjective Route Robust Optimization Model and Algorithm for Hazmat Transportation

Discrete Dynamics in Nature and Society, 2018
Aiming at route optimization problem of hazardous materials transportation in uncertain environment, this paper presents a multiobjective robust optimization model by taking robust control parameters into consideration.
Changxi Ma, Wei Hao, Ruichun He, Bahman Moghimi   +3 more
doaj   +1 more source