Results 71 to 80 of about 1,105,335 (289)

Batch Process Scheduling under Uncertainty using Data-Driven Multistage Adaptive Robust Optimization

open access: yesChemical Engineering Transactions, 2017
This paper proposes a novel data-driven batch process scheduling approach based on multistage adaptive robust optimization coupled with robust kernel density estimation (RKDE).
C. Ning, F. You
doaj   +1 more source

A Powerful Optimization Tool for Analog Integrated Circuits Design [PDF]

open access: yes, 2013
This paper presents a new optimization tool for analog circuit design. Proposed tool is based on the robust version of the differential evolution optimization method. Corners of technology, temperature, voltage and current supplies are taken into account
Jakovenko, J., Kubar, M.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Applying Robust Optimization to Solve Product Mix Problem in Automotive Industries [PDF]

open access: yesمدیریت صنعتی, 2009
Applying Robust Optimization to Solve Product Mix Problem in Automotive Industries In this article, applying robust optimization in product mix problem in automotive industries is presented.
Ali Mohaghar   +2 more
doaj  

Resilient Distributed Optimization Algorithms for Resource Allocation [PDF]

open access: yes, 2019
Distributed algorithms provide flexibility over centralized algorithms for resource allocation problems, e.g., cyber-physical systems. However, the distributed nature of these algorithms often makes the systems susceptible to man-in-the-middle attacks ...
Alizadeh, Mahnoosh   +2 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

A bicriteria approach to robust optimization [PDF]

open access: yesComputers & Operations Research, 2016
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
André B. Chassein, Marc Goerigk
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Robustness and Regularization of Support Vector Machines [PDF]

open access: yes, 2008
We consider regularized support vector machines (SVMs) and show that they are precisely equivalent to a new robust optimization formulation. We show that this equivalence of robust optimization and regularization has implications for both algorithms, and
Caramanis, Constantine   +2 more
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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