Results 71 to 80 of about 315,736 (266)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Applying Robust Optimization to Solve Product Mix Problem in Automotive Industries [PDF]
مدیریت صنعتی, 2009 Applying Robust Optimization to Solve Product Mix Problem in Automotive Industries In this article, applying robust optimization in product mix problem in automotive industries is presented.
Ali Mohaghar +2 more
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Optimization of HILIC method for the analysis of bisoprolol and its impurities considering uncertainties in peak position [PDF]
Arhiv za farmaciju, 2014 This paper presents the robust optimization of hydrophilic interaction liquid chromatographic method for the analysis of bisoprolol and its impurities A and C.
Rakić Tijana +4 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Batch Process Scheduling under Uncertainty using Data-Driven Multistage Adaptive Robust Optimization
Chemical Engineering Transactions, 2017 This paper proposes a novel data-driven batch process scheduling approach based on multistage adaptive robust optimization coupled with robust kernel density estimation (RKDE).
C. Ning, F. You
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Differential Evolution in Robust Optimization Over Time Using a Survival Time Approach
Mathematical and Computational Applications, 2020 This study presents an empirical comparison of the standard differential evolution (DE) against three random sampling methods to solve robust optimization over time problems with a survival time approach to analyze its viability and performance capacity ...
José-Yaír Guzmán-Gaspar +2 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Assessment of IMPT versus VMAT plans using different uncertainty scenarios for prostate cancer
Radiation Oncology, 2022 Background To assess the impact of systematic setup and range uncertainties for robustly optimized (RO) intensity modulated proton therapy (IMPT) and volumetric modulated arc therapy (VMAT) plans in patients with localized prostate cancer. Methods Twenty-
Michael P. Butkus +8 more
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