Results 131 to 140 of about 4,199,571 (295)
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Bidirectional-nonlinear threshold switching behaviors and thermally robust stability of ZnTe selectors by nitrogen annealing. [PDF]
Sci Rep, 2020 Jang G +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Robust stability of interval polynomials and matrices for linear systems
, 2010 This paper addresses on the robust stability problem of interval polynomials and matrices of the continuous-time linear system (C-TLS) and discrete-time linear system (D-TLS) that contain the real uncertain parameters.
Li XH(李先宏) +3 more
core
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Robust Stability of Interconnections
, 2006 We begin by observing that the graph topology with its various metrizations plays a fundamental role in the theory of robust stability for classical LTI systems([1, 2, 6].
Bian, Wenming +5 more
core
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Study on robust stability inverse problem for linear systems
, 2014 Most of traditional robust problems focus on developing a robust controller to stabilize the dynamic system when system parameters perturb in certain bounded range.
Li XH(李先宏) +3 more
core
Robust stability of trait-like vulnerability or resilience to common types of sleep deprivation in a large sample of adults. [PDF]
Sleep, 2020 Yamazaki EM, Goel N.
europepmc +1 more source