Results 11 to 20 of about 548,676 (308)
Evolution of Robustness in Growing Random Networks
Entropy, 2023 Networks are widely used to model the interaction between individual dynamic systems. In many instances, the total number of units and interaction coupling are not fixed in time, and instead constantly evolve.
Melvyn Tyloo
doaj +4 more sources
Evolution of robustness in digital organisms [PDF]
Artificial Life, 2004 We study the evolution of robustness in digital organisms adapting to a high mutation rate. As genomes adjust to the harsh mutational environment, the mean effect of single Imitations decreases, up until the point where a sizable fraction (up to 30% in ...
Adami, Christoph, Edlund, Jeffrey A.
core +5 more sources
Evolution of drift robustness in small populations [PDF]
Nature Communications, 2017 Genetic drift can reduce fitness in small populations by counteracting selection against deleterious mutations. Here, LaBar and Adami demonstrate through a mathematical model and simulations that small populations tend to evolve to drift-robust fitness ...
Thomas LaBar, Christoph Adami
doaj +3 more sources
The Effect of Recombination on the Neutral Evolution of Genetic Robustness [PDF]
Mathematical Biosciences, 2008 Conventional population genetics considers the evolution of a limited number of genotypes corresponding to phenotypes with different fitness. As model phenotypes, in particular RNA secondary structure, have become computationally tractable, however, it ...
Albert +17 more
core +3 more sources
Mutational robustness changes during long-term adaptation in laboratory budding yeast populations
eLife, 2022 As an adapting population traverses the fitness landscape, its local neighborhood (i.e., the collection of fitness effects of single-step mutations) can change shape because of interactions with mutations acquired during evolution.
Milo S Johnson, Michael M Desai
doaj +1 more source
Pangenome Evolution Reconciles Robustness and Instability of Rhizobial Symbiosis
mBio, 2022 Root nodulating rhizobia are nearly ubiquitous in soils and provide the critical service of nitrogen fixation to thousands of legume species, including staple crops.
Alexandra J. Weisberg +5 more
doaj +1 more source
Punctuated evolution and robustness in morphogenesis [PDF]
Biosystems, 2014 This paper presents an analytic approach to the pattern stability and evolution problem in morphogenesis. The approach used here is based on the ideas from the gene and neural network theory. We assume that gene networks contain a number of small groups of genes (called hubs) controlling morphogenesis process.
D, Grigoriev +3 more
openaire +2 more sources
Evolution under fluctuating environments explains observed robustness in metabolic networks. [PDF]
PLoS Computational Biology, 2010 A high level of robustness against gene deletion is observed in many organisms. However, it is still not clear which biochemical features underline this robustness and how these are acquired during evolution.
Orkun S Soyer, Thomas Pfeiffer
doaj +1 more source
Does mutational robustness inhibit extinction by lethal mutagenesis in viral populations? [PDF]
PLoS Computational Biology, 2010 Lethal mutagenesis is a promising new antiviral therapy that kills a virus by raising its mutation rate. One potential shortcoming of lethal mutagenesis is that viruses may resist the treatment by evolving genomes with increased robustness to mutations ...
Eamon B O'Dea +2 more
doaj +1 more source
A Role for Selection in the Evolution of Genetic Robustness.
PLoS Biology, 2005 doaj +3 more sources