Results 21 to 30 of about 567,669 (271)

Shaping robust system through evolution [PDF]

open access: yesChaos: An Interdisciplinary Journal of Nonlinear Science, 2008
Biological functions are generated as a result of developmental dynamics that form phenotypes governed by genotypes. The dynamical system for development is shaped through genetic evolution following natural selection based on the fitness of the phenotype.
openaire   +3 more sources

Robustness of adiabatic quantum computation [PDF]

open access: yes, 2001
We study the fault tolerance of quantum computation by adiabatic evolution, a quantum algorithm for solving various combinatorial search problems. We describe an inherent robustness of adiabatic computation against two kinds of errors, unitary control ...
Andrew M. Childs   +13 more
core   +2 more sources

Effects of ploidy and recombination on evolution of robustness in a model of the segment polarity network. [PDF]

open access: yesPLoS Computational Biology, 2009
Many genetic networks are astonishingly robust to quantitative variation, allowing these networks to continue functioning in the face of mutation and environmental perturbation. However, the evolution of such robustness remains poorly understood for real
Kerry J Kim, Vilaiwan M Fernandes
doaj   +1 more source

Evolution of Robustness to Protein Mistranslation by Accelerated Protein Turnover. [PDF]

open access: yesPLoS Biology, 2015
Translational errors occur at high rates, and they influence organism viability and the onset of genetic diseases. To investigate how organisms mitigate the deleterious effects of protein synthesis errors during evolution, a mutant yeast strain was ...
Dorottya Kalapis   +10 more
doaj   +1 more source

Selection to minimise noise in living systems and its implications for the evolution of gene expression

open access: yesMolecular Systems Biology, 2008
Gene expression, like many biological processes, is subject to noise. This noise has been measured on a global scale, but its general importance to the fitness of an organism is unclear.
Ben Lehner
doaj   +1 more source

EvoRSR: an integrated system for exploring evolution of RNA structural robustness

open access: yesBMC Bioinformatics, 2009
Background Robustness, maintaining a constant phenotype despite perturbations, is a fundamental property of biological systems that is incorporated at various levels of biological complexity.
Ni Ming   +4 more
doaj   +1 more source

Idealised simulations of cyclones with robust symmetrically-unstable sting jets [PDF]

open access: yes, 2020
Idealised simulations of Shapiro-Keyser cyclones developing a sting jet (SJ) are presented. Thanks to an improved and accurate implementation of thermal wind balance in the initial state, it has been possible to use more realistic environments than in ...
Clark, Peter A.   +2 more
core   +1 more source

Evolution of Robustness and Plasticity under Environmental Fluctuation: Formulation in terms of Phenotypic Variances [PDF]

open access: yes, 2012
The characterization of plasticity, robustness, and evolvability, an important issue in biology, is studied in terms of phenotypic fluctuations. By numerically evolving gene regulatory networks, the proportionality between the phenotypic variances of ...
Kaneko, Kunihiko
core   +2 more sources

PERSPECTIVE: EVOLUTION AND DETECTION OF GENETIC ROBUSTNESS [PDF]

open access: yesEvolution, 2003
Robustness is the invariance of phenotypes in the face of perturbation. The robustness of phenotypes appears at various levels of biological organization, including gene expression, protein folding, metabolic flux, physiological homeostasis, development, and even organismal fitness.
de Visser, J.A.G.M.   +18 more
openaire   +4 more sources

Recombination drives the evolution of mutational robustness [PDF]

open access: yesCurrent Opinion in Systems Biology, 2019
Recombination can impose fitness costs as beneficial parental combinations of alleles are broken apart, a phenomenon known as recombination load. Computational models suggest that populations may evolve a reduced recombination load by reducing either the likelihood of recombination events (bring interacting loci in physical proximity) or the strength ...
Sonia, Singhal   +2 more
openaire   +2 more sources

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