Results 61 to 70 of about 562,963 (309)

Fundamental Properties of the Evolution of Mutational Robustness [PDF]

, 2015
Evolution on neutral networks of genotypes has been found in models to concentrate on genotypes with high mutational robustness, to a degree determined by the topology of the network.
Altenberg, Lee
core  

Evolution Equation of Phenotype Distribution: General Formulation and Application to Error Catastrophe

, 2006
An equation describing the evolution of phenotypic distribution is derived using methods developed in statistical physics. The equation is solved by using the singular perturbation method, and assuming that the number of bases in the genetic sequence is ...
A. E. Mayo, A. Kashiwagi, E. Akin, E. Baake, H. A. Orr, H. Haken, H. Risken, J. F. Crow, J. Hofbauer, John G. Kemeny, K. Kaneko, Katsuhiko Sato, Kunihiko Kaneko, M. S. Waterman, N. G. van Kampen, P. M. Morse, R. E. Lenski, S. Kauffman   +17 more
core   +1 more source

Physical evolution in Loop Quantum Cosmology: The example of vacuum Bianchi I [PDF]

, 2009
We use the vacuum Bianchi I model as an example to investigate the concept of physical evolution in Loop Quantum Cosmology (LQC) in the absence of the massless scalar field which has been used so far in the literature as an internal time.
Martin-Benito, Mercedes, Marugan, Guillermo A. Mena, Pawlowski, Tomasz   +2 more
core   +3 more sources

In silico genetic robustness analysis of microRNA secondary structures: potential evidence of congruent evolution in microRNA

BMC Evolutionary Biology, 2007
Background Robustness is a fundamental property of biological systems and is defined as the ability to maintain stable functioning in the face of various perturbations.
Ni Ming, Bo Xiaochen, Shu Wenjie, Zheng Zhiqiang, Wang Shengqi   +4 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Evolvability and Robustness in Populations of RNA Virus Φ6

Frontiers in Microbiology, 2014
Microbes can respond quickly to environmental disturbances through adaptation. However, processes determining the constraints on this adaptation are not well understood.
Daniel eGoldhill, Angela eLee, Elizabeth S. C. P. Williams, Paul E Turner   +3 more
doaj   +1 more source

Scale-free networks are not robust under neutral evolution

, 2001
Recently it has been shown that a large variety of different networks have power-law (scale-free) distributions of connectivities. We investigate the robustness of such a distribution in discrete threshold networks under neutral evolution.
Bollobás B., Bornholdt S., Darwin C., Derrida B., Kauffman S. A., Kimura M., Kürten K. E., M Hörnquist   +7 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Robustness in numerical computations of damage evolution in cohesive-frictional materials

Computer Assisted Methods in Engineering and Science, 2023
Numerical simulations of the mechanical behaviour of structures composed of cohesive-frictional materials such as soils, concrete and rocks, still suffer from a lack of robustness.
René de Borst
doaj  

Robustness of the long-term nonlinear evolution of global sea surface temperature trend

Geoscience Letters, 2022
The multi-scale variability of global sea surface temperature (GSST), which is often dominated by secular trends, significantly impacts global and regional climate change. Previous studies were mainly carried out under linear assumptions.
Zhenhao Xu, Gang Huang, Fei Ji, Bo Liu, Fei Chang, Xichen Li   +5 more
doaj   +1 more source