Results 91 to 100 of about 143,227 (288)
ON FORMATION OF ELECTRICALLY CONDUCTIVE PHASES UNDER ELECTROTHERMAL ACTIVATION OF FERRUGINOUS CARBONATES [PDF]
, 2017 Purpose. Study of the formation of an electrically conductive phase in carbonates using siderite as an example and determination of the temperature dependence of its formation and silicon content during simultaneous heating and the action of a weak ...
Bilan, N.V. +2 more
core
Proton FLASH Exposure Preserves Gut Commensal Microbiomes and Spares Intestinal Stem Cells
Advanced Science, EarlyView.This study highlights the role of Proton FLASH abdominal irradiation in sparing of intestinal stem cells and preservation of key gut microbial population resulting minimization of radiation toxicity in intestinal epithelium in mice. Our findings support the potential of Proton FLASH to improve the therapeutic ratio for abdominal radiation exposure ...
Rishi Man Chugh +11 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Base editors enable precise genome modification and have emerged as a promising therapeutic approach for correcting diseases caused by single‐nucleotide variants. While the current efficient version of adenine base editors (ABEs), such as ABE8e, exhibits exceptional efficiency for A‐to‐G conversions, their clinical translation is hindered by ...
Jiawei Yao +12 more
wiley +1 more source
Advanced Science, EarlyView.Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang +11 more
wiley +1 more source
Advanced Science, EarlyView.This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang +10 more
wiley +1 more source
PRINCIPLES OF ROCK PRESSURE ENERGY USAGE DURING UNDERGROUND MINING OF DEPOSITS [PDF]
, 2017 Purpose. To substantiate principles of rock pressure usage during underground mining of deposits. Methodology. Zonal structuring indices of massif around mine workings were established with help of industrial, laboratory and theoretical research of ...
Khomenko, O. Ye +3 more
core
Advanced Science, EarlyView.A stable Ti3C2Clx/Ti3ZnC2 heterostructure, fabricated by dynamic etching, exhibits outstanding electrocatalytic NRR activity (NH3 yield: 20.1 µg h−1 mg−1, FE: 38.1%) in alkaline media. The corresponding Zn‐N2 battery achieves a peak power density of 36.5 µW cm−2 and an NH3 yield of 13.1 µg h−1 mg−1, providing an advanced strategy for NH3 and ...
Yu Wang +9 more
wiley +1 more source
The chemical bond as an emergent phenomenon
, 2017 We first argue that the covalent bond and the various closed-shell interactions can be thought of as symmetry broken versions of one and the same interaction, viz., the multi-center bond.
Golden, Jon C. +2 more
core +1 more source
Advanced Science, EarlyView.Magnetoelectric nanoparticles (MENPs) enable fully wireless, minutely invasive neuromodulation, and potentially neural recording, by converting magnetic into electric and, conversely, electric into magnetic fields, respectively, at high spatiotemporal resolution.
Elric Zhang +14 more
wiley +1 more source